China Factory Direct
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| CAS number | 101803-06-9 |
| Product name | 5-Iodo-2-methoxypyrimidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for antiviral drug synthesis | Prepared via nucleophilic substitution of 2-methoxy-5-halopyrimidine with an iodinating reagent (e.g., sodium iodide or potassium iodide) in a polar solvent |
| Pharmaceuticals | Precursor for nitrogen-containing heterocyclic compounds | Serves as an aryl iodide substrate in coupling reactions (e.g., Suzuki or Buchwald–Hartwig) to form C–C or C–N bonds |
| Agrochemicals | Intermediate for novel selective herbicide synthesis | Undergoes nucleophilic substitution with amino- or thiol-containing compounds to construct biologically active pyrimidine derivatives |
| Materials Science | Building block for organic semiconductors or luminescent materials | Functions as an iodinated aromatic heterocyclic component in transition metal-catalyzed polymerization to produce functionalized conjugated polymers |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., des-iodo, nitro, or hydrolysis products) via gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Measures residual solvents (e.g., methanol, THF, toluene) by headspace GC with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Determines water content volumetrically using iodine-based redox titration in anhydrous methanol/pyridine medium. |
| Heavy Metals | ICP-MS | Quantifies trace heavy metals (Pb, Cd, Hg, As) after acid digestion using inductively coupled plasma mass spectrometry with isotope dilution. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content by ignition at 700-800 C followed by precise weighing of residual residue. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and homogeneity of bulk sample against established visual reference standards under controlled lighting. |
| Particle Size Distribution | Laser Diffraction | Measures particle size distribution in dry powder form using Mie scattering theory and calibrated optical model. |
| Bulk Density | Tap Density Tester | Determines mass per unit volume after standardized mechanical tapping per USP <616>. |
| Microbial Limits | Membrane Filtration | Detects aerobic microorganisms and specified pathogens (e.g., E. coli, S. aureus) by filtration, culture on selective media, and colony enumeration. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 112–116°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.