China Factory Direct
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| CAS number | 1022094-01-4 |
| Product name | (S)-N-Boc-3-Methylmorpholine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key chiral intermediate in the synthesis of chiral drugs, used to construct morpholine-containing active pharmaceutical ingredients (e.g., kinase inhibitors) | Employed as a chiral auxiliary in asymmetric synthesis, or coupled with carboxylic acid derivatives to form amide bonds after deprotection |
| Pharmaceutical R&D | Used for screening and optimizing targeted candidate compounds, particularly inhibitors of signaling pathways such as PI3K/AKT/mTOR | Integrated as a structural diversity module in combinatorial library construction, introduced into target molecular scaffolds via solid-phase or solution-phase multistep synthesis |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at characteristic wavelength. |
| Enantiomeric Purity | Chiral HPLC | Resolves (S)- and (R)-enantiomers on a chiral stationary phase; peak area ratio determines enantiomeric excess. |
| Residual Solvents | GC-FID | Separates and quantifies volatile organic solvents by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Measures water via coulometric or volumetric titration using iodine-based redox reaction. |
| Heavy Metals | ICP-MS | Detects trace metal impurities (e.g., Pb, Cd, Ni) by inductively coupled plasma mass spectrometry. |
| Residual Palladium | ICP-OES | Quantifies palladium from catalytic hydrogenation steps using inductively coupled plasma optical emission spectroscopy. |
| Chloride Impurity | Ion Chromatography | Separates and detects chloride ions based on anion exchange and conductivity detection. |
| Sulfate Impurity | Ion Chromatography | Separates and detects sulfate ions using anion exchange chromatography with suppressed conductivity detection. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of visible particulates under controlled lighting conditions. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary apparatus. |
| Loss on Drying | Gravimetric Analysis | Measures weight loss after heating under specified temperature and vacuum to determine volatile content. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light to confirm chiral integrity and concentration-dependent specific rotation. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Optical Rotation | -15.0 to -18.0 deg (c=1, in CHCl3) |
| Melting Point | 78.0 to 82.0 °C |
| Identification (NMR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.