China Factory Direct
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| CAS number | 102212-98-6 |
| Product name | 5'-O-DMT-N4-Benzoyl-2'-deoxycytidine 3'-CE phosphoramidite |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Biopharmaceuticals | Oligonucleotide synthesis (e.g., DNA primers, probes) | Used in solid-phase phosphoramidite triester synthesis |
| Scientific Research | Custom DNA sequence preparation (e.g., for PCR, sequencing) | Performed on automated DNA synthesizers |
| Molecular Diagnostics | Production of fluorescently labeled probes | Applied in chemically modified nucleotide assembly |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 260 nm, calibrated against certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities by gradient HPLC-UV; identification based on retention time and relative response factors. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents (e.g., acetonitrile, dichloromethane) per ICH Q3C. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content in non-aqueous matrix. |
| Acid Value | Acid-Base Titration | Titration with standardized KOH solution in isopropanol/toluene to quantify free acidic impurities (e.g., phosphonic acid derivatives). |
| Phosphorus Content | ICP-OES | Digestion followed by inductively coupled plasma optical emission spectroscopy to verify stoichiometric P content. |
| Chloride Ion | Ion Chromatography | Separation on anion-exchange column with conductivity detection to quantify chloride from synthesis residues. |
| Heavy Metals | ICP-MS | Microwave-assisted digestion and ultra-trace quantification of Pb, Cd, Hg, As, and Ni per ICH Q3D. |
| Optical Rotation | [alpha]D Measurement | Polarimetric measurement at 589 nm to confirm chiral integrity and enantiomeric purity. |
| Particle Size Distribution | Laser Diffraction | Dry dispersion and light scattering analysis to assess bulk handling and dissolution consistency. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition detection via controlled heating rate to verify crystalline identity and purity. |
| Residual Palladium | ICP-MS | Quantification of Pd catalyst residue after microwave digestion, critical for oligonucleotide synthesis compatibility. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Optical Rotation | +35.0 to +38.0 deg (c=1, CHCl3) |
| Solubility | Freely soluble in anhydrous acetonitrile and dichloromethane |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.