BIS(2-CYANOETHYL)-N,N-DIISOPROPYL PHOSPHORAMIDITE Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 102690-88-0 |
| Product name | BIS(2-CYANOETHYL)-N,N-DIISOPROPYL PHOSPHORAMIDITE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for BIS(2-CYANOETHYL)-N,N-DIISOPROPYL PHOSPHORAMIDITE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk BIS(2-CYANOETHYL)-N,N-DIISOPROPYL PHOSPHORAMIDITE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of BIS(2-CYANOETHYL)-N,N-DIISOPROPYL PHOSPHORAMIDITE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in nucleotide synthesis for solid-phase synthesis of oligonucleotides and antisense oligonucleotides | Used as a phosphoramidite reagent in solid-phase synthesis; reacts with nucleoside solid supports to form phosphotriester bonds, followed by oxidation to yield stable phosphodiester bonds |
| Biotechnology | Synthesis of functional nucleic acid therapeutics, including siRNA, miRNA mimics, and aptamers | Employed as a phosphoramidite monomer in automated DNA/RNA synthesizers; participates in stepwise coupling reactions to construct sequence-specific nucleic acid chains |
| Chemical Synthesis | Highly selective phosphorylating agent for organic phosphorus compound synthesis | Reacts with hydroxyl-containing compounds under anhydrous conditions to form phosphorus–oxygen bonds, enabling construction of phosphorus-containing functional molecules |
Manufacturing Quality Control of BIS(2-CYANOETHYL)-N,N-DIISOPROPYL PHOSPHORAMIDITE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 210 nm. |
| Related Substances | HPLC-UV | Separation and detection of impurities using gradient HPLC with UV detection; identification and quantification relative to main peak. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., THF, toluene, dichloromethane). |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generation in pyridine/methanol-based reagent; based on stoichiometric water-iodine reaction. |
| Acidity (as H3PO4) | Acid-Base Titration | Titration with standardized sodium hydroxide solution using phenolphthalein or potentiometric endpoint detection. |
| Phosphorus Content | ICP-OES | Quantitative determination of total phosphorus after acid digestion by measuring characteristic emission wavelength intensity. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element detection after microwave-assisted acid digestion; based on mass-to-charge ratio measurement of metal isotopes. |
| Chloride Impurity | Ion Chromatography | Separation of chloride anions on anion-exchange column with suppressed conductivity detection. |
| Optical Rotation | [alpha]D Measurement | Determination of specific rotation using sodium D-line light source in a polarimeter; indicative of chiral purity. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed as solid-to-liquid phase change under controlled heating rate. |
| Residue on Ignition | Gravimetric Analysis | Mass of non-volatile residue after high-temperature ashing at 500-600 C, expressed as percentage of sample weight. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against established reference standards under controlled lighting conditions. |
Technical Specifications of BIS(2-CYANOETHYL)-N,N-DIISOPROPYL PHOSPHORAMIDITE
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Odor | Characteristic odor |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of BIS(2-CYANOETHYL)-N,N-DIISOPROPYL PHOSPHORAMIDITE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of BIS(2-CYANOETHYL)-N,N-DIISOPROPYL PHOSPHORAMIDITE
Safety Information of BIS(2-CYANOETHYL)-N,N-DIISOPROPYL PHOSPHORAMIDITE
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of BIS(2-CYANOETHYL)-N,N-DIISOPROPYL PHOSPHORAMIDITE
Industrial BIS(2-CYANOETHYL)-N,N-DIISOPROPYL PHOSPHORAMIDITE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply