ethyl 1-benzyl-4-oxo-pyrrolidine-3-carboxylate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1027-35-6 |
| Product name | ethyl 1-benzyl-4-oxo-pyrrolidine-3-carboxylate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for ethyl 1-benzyl-4-oxo-pyrrolidine-3-carboxylate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk ethyl 1-benzyl-4-oxo-pyrrolidine-3-carboxylate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of ethyl 1-benzyl-4-oxo-pyrrolidine-3-carboxylate
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used in the synthesis of antihistamines, anti-allergy agents, and neurosystem-related compounds | Serves as a key intermediate in multistep organic synthesis, including reduction, condensation, and cyclization reactions |
| Organic Synthesis | Acts as a precursor for constructing nitrogen-containing heterocyclic structures | Introduces the target molecular scaffold via functional group transformations, such as ketone reduction or ester hydrolysis/ammonolysis |
| Drug Discovery | Serves as a lead compound or structural modification template for new drug screening | Supports structure–activity relationship (SAR) studies in medicinal chemistry to optimize potency and selectivity |
Manufacturing Quality Control of ethyl 1-benzyl-4-oxo-pyrrolidine-3-carboxylate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 210-230 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC with UV detection; identification based on retention time relative to reference standards. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify common organic solvents (e.g., ethanol, ethyl acetate, toluene) based on calibrated response factors. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content via stoichiometric reaction with water. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry for ultra-trace sensitivity. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions in solution after sample dissolution and dilution; quantified against chloride standard calibration. |
| Sulfated Ash | Gravimetric Analysis | Incineration at 500-600 C followed by sulfuric acid treatment and final ash weighing to determine inorganic residue content. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific rotation using a polarimeter at 20 C with sodium D-line (589 nm) to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, indicating crystallinity and presence of impurities. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Electrochemical measurement using calibrated pH electrode in a saturated aqueous suspension to assess acidic/basic degradation products. |
| Residual Catalyst (Pd) | ICP-OES | Quantification of palladium after microwave-assisted acid digestion using inductively coupled plasma optical emission spectroscopy. |
| Microbial Limits | Membrane Filtration and Plate Count | Enumeration of aerobic microorganisms via filtration, membrane transfer to culture media, and colony counting after incubation per Ph. Eur. 2.6.12. |
Technical Specifications of ethyl 1-benzyl-4-oxo-pyrrolidine-3-carboxylate
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128–132°C |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
| Optical Rotation | -15.0 to -19.0° (c=1, in CHCl3) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of ethyl 1-benzyl-4-oxo-pyrrolidine-3-carboxylate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of ethyl 1-benzyl-4-oxo-pyrrolidine-3-carboxylate
Safety Information of ethyl 1-benzyl-4-oxo-pyrrolidine-3-carboxylate
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of ethyl 1-benzyl-4-oxo-pyrrolidine-3-carboxylate
Industrial ethyl 1-benzyl-4-oxo-pyrrolidine-3-carboxylate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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