4-PHENYLPIPERIDINE HYDROCHLORIDE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 10272-49-8 |
| Product name | 4-PHENYLPIPERIDINE HYDROCHLORIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-PHENYLPIPERIDINE HYDROCHLORIDE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-PHENYLPIPERIDINE HYDROCHLORIDE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-PHENYLPIPERIDINE HYDROCHLORIDE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of opioid analgesics (e.g., pethidine, benperidol) | Used in drug synthesis to construct piperidine-containing active molecular scaffolds via nucleophilic substitution, reductive amination, or acylation |
| Chemical Research | Structural modification and structure–activity relationship (SAR) studies in organic synthesis | Applied as a nitrogen-containing heterocyclic building block in multicomponent reactions and metal-catalyzed coupling reactions for complex molecule library construction |
| Pharmaceutical R&D | Lead structure for developing central nervous system (CNS)-targeted compounds | Supplied as the hydrochloride salt to enhance aqueous solubility and stability, facilitating subsequent formulation development and biological activity testing |
Manufacturing Quality Control of 4-PHENYLPIPERIDINE HYDROCHLORIDE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 210-230 nm, comparing peak area to reference standard. |
| Related Substances | HPLC-DAD | Detects and quantifies impurities by HPLC with diode array detection, using gradient elution and comparison to qualified reference standards. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., ethanol, acetone) by gas chromatography with flame ionization detection using headspace sampling. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine-based reagent reacting stoichiometrically with water. |
| Heavy Metals | ICP-MS | Quantifies Pb, Cd, Hg, As, and other toxic elements at sub-ppb levels using inductively coupled plasma mass spectrometry after acid digestion. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after anion exchange separation. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing (700-800 C) and weighing of the cooled crucible. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determines acidity/basicity of a 1% w/v aqueous suspension using calibrated pH electrode and standardized buffer solutions. |
| Melting Point | Capillary Melting Point Apparatus | Identifies purity and identity by measuring temperature range at which solid transitions to liquid under controlled heating rate. |
| Specific Optical Rotation | Polarimetry | Measures chiral purity and identity by determining rotation angle of plane-polarized light passing through a solution at specified concentration and wavelength. |
| Particle Size Distribution | Laser Diffraction | Characterizes solid particle size by analyzing angular scattering pattern of laser beam passed through dispersed sample. |
| Microbial Limits | Membrane Filtration and Culture | Detects aerobic microorganisms, yeasts, and molds by filtration, membrane transfer to selective agar media, and colony enumeration after incubation. |
Technical Specifications of 4-PHENYLPIPERIDINE HYDROCHLORIDE
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 218-222°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-PHENYLPIPERIDINE HYDROCHLORIDE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-PHENYLPIPERIDINE HYDROCHLORIDE
Safety Information of 4-PHENYLPIPERIDINE HYDROCHLORIDE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-PHENYLPIPERIDINE HYDROCHLORIDE
Industrial 4-PHENYLPIPERIDINE HYDROCHLORIDE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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