1-Bromo-2-chloro-5-fluoro-4-nitrobenzene Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1027833-17-5 |
| Product name | 1-Bromo-2-chloro-5-fluoro-4-nitrobenzene |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-Bromo-2-chloro-5-fluoro-4-nitrobenzene
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-Bromo-2-chloro-5-fluoro-4-nitrobenzene Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-Bromo-2-chloro-5-fluoro-4-nitrobenzene
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used in the synthesis of active pharmaceutical ingredients (APIs), including antitumor agents and kinase inhibitors | Introduces aryl or alkenyl groups via palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck), followed by reduction, diazotization, and other steps to construct the target molecular scaffold |
| Agrochemical Intermediates | Serves as a key structural unit in novel insecticides and fungicides | Undergoes nucleophilic substitution or metal-catalyzed coupling to build fluorinated, chlorinated, or brominated heterocyclic or aniline-based agrochemical molecules |
| Materials Science | Used to prepare high-performance organic optoelectronic materials (e.g., hole-transport layers for OLEDs) | Links electron-donating groups—such as carbazole and triphenylamine—via Ullmann coupling or Buchwald-Hartwig amination to form thermally stable, high-mobility conjugated molecules |
Manufacturing Quality Control of 1-Bromo-2-chloro-5-fluoro-4-nitrobenzene
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities based on retention time and relative response factors versus main component. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content in the sample. |
| Heavy Metals | ICP-OES | Multi-element determination of Pb, Cd, Hg, As, and others after acid digestion, based on atomic emission intensity. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction. |
| Residual Catalyst (Pd) | ICP-MS | Ultra-trace palladium quantification following microwave-assisted digestion and isotopic mass spectrometry detection. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled white light. |
| Loss on Drying | Gravimetric Analysis | Mass loss determination after drying at specified temperature and vacuum, per USP <731>. |
| Acid-Base Impurities | Acid-Base Titration | Titration with standardized NaOH or HCl to detect residual acidic or basic process-related impurities. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using Mie scattering theory to determine D10, D50, D90 values. |
Technical Specifications of 1-Bromo-2-chloro-5-fluoro-4-nitrobenzene
| Test Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 102–106 °C |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-Bromo-2-chloro-5-fluoro-4-nitrobenzene
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-Bromo-2-chloro-5-fluoro-4-nitrobenzene
Safety Information of 1-Bromo-2-chloro-5-fluoro-4-nitrobenzene
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 1-Bromo-2-chloro-5-fluoro-4-nitrobenzene
Industrial 1-Bromo-2-chloro-5-fluoro-4-nitrobenzene Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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