1-Amino-2-methylindoline hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 102789-79-7 |
| Product name | 1-Amino-2-methylindoline hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-Amino-2-methylindoline hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-Amino-2-methylindoline hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-Amino-2-methylindoline hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate in the synthesis of active pharmaceutical ingredients (APIs), including antidepressants and antipsychotics | Prepared via aminomethylation and hydrochloride salt formation of the indoline ring |
| Organic Synthesis | Employed to construct complex nitrogen-containing heterocyclic structures; serves as a starting material for analog synthesis | Functional groups are introduced via nucleophilic substitution and cyclization-condensation reactions |
| Polymer Materials | Applied as a functional monomer in the development of high-performance polymers containing nitrogen-containing heterocycles | Incorporated into polymer chains via free-radical polymerization or condensation polymerization |
| Fine Chemicals | Utilized in the synthesis of dyes, catalyst ligands, and functional additives | Functionalized via coupling reactions or coordination-based modification |
Manufacturing Quality Control of 1-Amino-2-methylindoline hydrochloride
| Detection Item | Common Detection Methods | Method Overview |
|---|---|---|
| Purity Analysis | High-Performance Liquid Chromatography (HPLC) | Utilizes a reversed-phase C18 column with mobile phases such as acetonitrile-water or methanol-phosphate buffer; detection is performed using a UV detector (e.g., 254 nm). Purity is assessed by comparing retention times with reference standards to calculate the content of the main component. |
| Content Determination | Titration (Non-aqueous Titration) | Exploits the basic nitrogen atom by performing non-aqueous titration using a perchloric acid-acetic acid system, with crystal violet as the indicator. The effective content is calculated based on the volume of standard titrant consumed, suitable for hydrochloride salts. |
| pH (Acidity/Alkalinity) | pH Meter Method | The sample is dissolved in an appropriate amount of water or buffer solution, and the pH is directly measured using a calibrated pH meter to ensure compliance with pharmacopoeial or corporate standards. |
| Water Content | Karl Fischer Titration (KF) | Utilizes volumetric or coulometric Karl Fischer titration instruments to determine water content with high accuracy, suitable for salts containing crystalline water or those prone to hygroscopy. |
| Related Substances / Impurity Testing | HPLC-UV or LC-MS | Building upon purity analysis, gradient elution conditions are employed to separate potential impurities. Coupled with mass spectrometric detection, unknown impurities can be structurally identified, aiding in the assessment of process stability and safety. |
| Ultraviolet-Visible Spectroscopy (UV-Vis) | UV-Visible Spectrophotometry | Measures characteristic absorption wavelengths (e.g., ~260–280 nm), compares spectra with reference standards to confirm molecular structural features, and assists in authenticity verification and basic purity assessment. |
| Infrared Spectroscopy (IR) | Fourier Transform Infrared Spectroscopy (FTIR) | Compares the infrared spectrum of the sample with that of a reference standard to analyze characteristic functional groups (e.g., —NH₂, —C=O, C—N bonds) for structural confirmation and identity verification. |
| Nuclear Magnetic Resonance (NMR) | ¹H NMR / ¹³C NMR | Sample is dissolved in deuterated solvents (e.g., DMSO-d6, CDCl₃); hydrogen or carbon spectra are obtained, and molecular structure integrity and purity are verified through chemical shifts, integration areas, and coupling constants. |
| Melting Point Determination | Microscopic Melting Point Apparatus | Uses a microscopic melting point instrument to measure the melting temperature range of the sample, comparing it with literature values to assess purity and detect possible impurities. |
| Heavy Metal Detection | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Following acid digestion, heavy metal residues such as lead, cadmium, and mercury are quantified using atomic absorption spectroscopy or inductively coupled plasma mass spectrometry to ensure compliance with pharmaceutical-grade standards. |
Technical Specifications of 1-Amino-2-methylindoline hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-Amino-2-methylindoline hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Safety Information of 1-Amino-2-methylindoline hydrochloride
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 1-Amino-2-methylindoline hydrochloride
Industrial 1-Amino-2-methylindoline hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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