4-Chloro-3-nitroanisole Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 10298-80-3 |
| Product name | 4-Chloro-3-nitroanisole |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Chloro-3-nitroanisole
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Chloro-3-nitroanisole Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Chloro-3-nitroanisole
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of antibiotics (e.g., chloramphenicol) | Reduced to 3-amino-4-chloroanisole, which serves as a building block for drug scaffolds |
| Chemicals | Intermediate for dye and organic pigment production | Used as an aromatic amine precursor; diazotized and coupled to introduce chromophores |
| Agrochemicals | Raw material for synthesizing certain pesticides or plant growth regulators | Chemically modified to construct bioactive molecules containing benzoheterocyclic structures |
Manufacturing Quality Control of 4-Chloro-3-nitroanisole
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-DAD | Separation and identification of impurities based on retention time and UV spectral match relative to reference standards or threshold limits. |
| Residual Solvents | GC-FID | Volatile organic solvents quantified by gas chromatography with flame ionization detection using internal standard calibration. |
| Moisture Content | Karl Fischer Titration | Coulometric or volumetric titration where iodine reacts stoichiometrically with water in a controlled anhydrous medium. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range over which solid transitions to liquid, indicating crystallinity and presence of impurities. |
| Chloride Content (inorganic) | Ion Chromatography (IC) | Separation and quantification of chloride ions using anion-exchange column and conductivity detection. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Elemental quantification after acid digestion by inductively coupled plasma mass spectrometry with isotope-specific detection. |
| Sulfated Ash | Gravimetric Analysis | Residue weight after incineration with sulfuric acid treatment, representing non-volatile inorganic impurities. |
| Residual Catalyst (e.g., Cu, Pd) | ICP-OES | Multi-element detection of metal catalyst residues after microwave-assisted acid digestion and plasma optical emission measurement. |
| p-Nitroanisole Impurity | GC-MS | Identification and quantification of this common side-product using retention time and mass spectral library matching. |
| 4-Chloro-3-nitrophenol Impurity | HPLC-UV | Detection and quantification of acidic degradation product via reversed-phase separation and UV absorbance at 270 nm. |
| Particle Size Distribution | Laser Diffraction | Measurement of scattered light intensity from dispersed particles to calculate volume-based size distribution. |
Technical Specifications of 4-Chloro-3-nitroanisole
| Test Item | Specification |
|---|---|
| Appearance | Brown solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 74–78°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Identification (IR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Chloro-3-nitroanisole
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Chloro-3-nitroanisole
Packaging of 4-Chloro-3-nitroanisole
Industrial 4-Chloro-3-nitroanisole Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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