China Factory Direct
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| CAS number | 103-85-5 |
| Product name | 1-PHENYL-2-THIOUREA |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Insecticide intermediate | Used in the synthesis of benzimidazole fungicides such as benomyl and thiophanate-methyl, via condensation and cyclization with o-phenylenediamine to form the benzimidazole ring structure |
| Pharmaceuticals | Pharmaceutical intermediate | Serves as a precursor in the synthesis of antithyroid agents (e.g., methimazole) and anticancer drugs, participating in heterocycle construction reactions |
| Rubber industry | Vulcanization accelerator | Added in small amounts to improve crosslinking efficiency and physical properties of vulcanized rubber compounds; commonly used in combination with other accelerators (e.g., thiazoles) |
| Electroplating | Surface treatment additive for metals | Functions as a brightener and leveling agent in copper and nickel plating baths, regulating metal deposition rate through adsorption onto the cathode surface |
| Analytical chemistry | Metal ion chelating agent | Employed in colorimetric determination of heavy metal ions such as copper, silver, and mercury, forming colored complexes for quantitative analysis |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Assay | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with methanol-water or acetonitrile-buffer solution as the mobile phase. Detection is performed using a UV detector (around 254 nm), and phenylthiourea content is quantified by external standard method, offering high sensitivity and excellent separation. |
| Purity Analysis | Gas Chromatography-Mass Spectrometry (GC-MS) | After appropriate derivatization, the sample is injected and separated by gas chromatography, followed by mass spectrometric detection to identify and semi-quantitatively analyze organic impurities, thereby assessing sample purity. |
| Residual Solvent Testing | Gas Chromatography (GC) | Based on pharmacopoeia methods (e.g., Chinese Pharmacopoeia, USP), headspace sampling combined with capillary gas chromatography is used to detect residual organic solvents (such as methanol, ethanol, acetone) from the manufacturing process. |
| Moisture Content Determination | Karl Fischer Titration | Employs an electrochemical titration principle to accurately measure trace moisture content in samples; suitable for quality control of raw materials sensitive to moisture. |
| Melting Point Determination | Melting Point Apparatus | Determines the melting temperature range of phenylthiourea using automated or manual melting point instruments, serving as a physical constant for identification and purity assessment. |
| Heavy Metals Testing | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Sample is digested and then analyzed for heavy metal elements such as lead, cadmium, mercury, and arsenic to ensure compliance with pharmaceutical or industrial safety standards. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Uses gradient or isocratic elution to detect organic impurities such as synthesis intermediates and degradation products in phenylthiourea. Typically requires individual impurities not exceeding 0.1% and total impurities not exceeding 0.5%. |
| Identification Test | Infrared Spectroscopy (IR) | The sample is mixed with potassium bromide and pressed into a pellet. The infrared absorption spectrum is measured and compared with a reference spectrum to confirm structural consistency, including characteristic peaks of functional groups such as N-H and C=S. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 148–152°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.