China Factory Direct
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| CAS number | 10310-21-1 |
| Product name | 6-Chloroguanine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Key intermediate for antiviral drugs Famciclovir and Penciclovir | Serves as starting material or key intermediate in constructing purine nucleoside analog structures via cyclization, substitution, or condensation reactions |
| Pharmaceutical Chemicals | Intermediate in the synthesis of antiviral drugs Acyclovir and Ganciclovir | Leverages reactivity of the 2-amino and 6-chloro groups for coupling or nucleophilic substitution with other side chains |
| Pharmaceutical Chemicals | Precursor synthesis for nucleoside-based antiviral agents | As a guanine derivative, participates in N-9 alkylation to introduce alkyl side chains and build the drug scaffold |
| Biochemical Engineering / Research | Biochemical reagent for molecular biology research | Used to synthesize modified nucleosides or as a tool molecule for enzyme inhibition in studies of purine metabolism pathways |
| Test Item | Common Testing Method | Method Overview |
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| Identification Test | Infrared Spectroscopy (IR) | Determine the infrared absorption spectrum of the sample and compare it with standard spectra to confirm the characteristic functional groups and structure of 2-amino-6-chloropurine. |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Analyze the chemical shifts and coupling constants of hydrogen atoms using nuclear magnetic resonance technology to verify the molecular structure. | |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 chromatographic column, with an appropriate mobile phase (such as methanol-water or acetonitrile-buffer salt system), and perform separation using a UV detector (usually near 254 nm) for quantitative analysis of the main component content. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Use gradient or isocratic elution procedures to separate and detect possible process impurities and degradation products. Calculate the impurity content using area normalization or self-comparison methods. |
| Dry Loss | Thermogravimetric Analysis (TGA) or Constant Pressure Drying Method | Dry the sample at a specified temperature (e.g., 105°C) until constant weight is achieved, and determine the percentage mass loss due to water or other volatile components. |
| Residual Ash | High-Temperature Incineration Method | Incinerate the sample at high temperatures (typically 700–800°C) and measure the weight of the residual inorganic material (ash) to assess the level of inorganic impurities. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace or direct injection methods with capillary columns for separation, and quantify residual organic solvents (such as methanol, dichloromethane, etc.) using FID or MS detectors. |
| pH Value | pH Meter Measurement Method | Prepare a certain concentration aqueous solution (e.g., 1%), and measure its acidity or alkalinity using a calibrated pH meter, reflecting product purity and potential acidic or basic impurities. |
| Melting Point | Melting Point Determination Method | Determine the temperature range from initial melting to complete melting using capillary or digital melting point apparatus as an auxiliary indicator for purity and identity verification. |
| Test Item | Specification |
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| Appearance | White to orange to green crystalline powder |
| Purity | >=98.0% (HPLC) |
| Melting Point | 275-279 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.