2-Chloro-5-nitropyrimidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 10320-42-0 |
| Product name | 2-Chloro-5-nitropyrimidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Chloro-5-nitropyrimidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Chloro-5-nitropyrimidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Chloro-5-nitropyrimidine
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate for synthesizing high-efficiency insecticides (e.g., flupyradifurone) | Undergoes nucleophilic substitution with phenylacetonitrile derivatives to construct the pyrimidinamine structure |
| Pharmaceuticals | Heterocyclic scaffold precursor for antitumor and antiviral drugs | Nitro group is reduced to amino, followed by derivatization—such as diazotization-coupling or acylation—to prepare active molecules |
| Dyes | Heterocyclic coupling component in azo and reactive dyes | Acts as a chlorinated nitro-heterocyclic acceptor in diazonium salt coupling reactions to generate colored compounds |
Manufacturing Quality Control of 2-Chloro-5-nitropyrimidine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time relative to reference standards or spiked samples. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, acetone, DMF) based on calibrated external standards. |
| Moisture Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content via stoichiometric reaction with water. |
| Heavy Metals | ICP-OES | Multi-element quantification after acid digestion, measuring emission intensities of metal atoms excited in plasma. |
| Chloride Ion Impurity | Ion Chromatography | Separation of anions on an ion-exchange column with conductivity detection; chloride quantified using calibration curve. |
| Sulfated Ash | Gravimetric Analysis | Incineration at 500-600 C followed by sulfuric acid treatment and final weighing of residual inorganic ash. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, observed visually under controlled heating rate. |
| Organic Volatile Impurities | GC-MS | Screening and semi-quantitative identification of unknown volatile impurities using mass spectral library matching and retention index comparison. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity patterns to calculate volume-based particle size distribution in dispersed dry or wet sample. |
| Bulk Density | ASTM D1895 | Measurement of mass per unit volume for freely settled powder using standardized cylinder and tapping procedure. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Determination of hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
Technical Specifications of 2-Chloro-5-nitropyrimidine
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 74.0–76.0 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Chloro-5-nitropyrimidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Chloro-5-nitropyrimidine
Packaging of 2-Chloro-5-nitropyrimidine
Industrial 2-Chloro-5-nitropyrimidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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