trans-4-Cyclohexyl-L-proline Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 103201-78-1 |
| Product name | trans-4-Cyclohexyl-L-proline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for trans-4-Cyclohexyl-L-proline
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk trans-4-Cyclohexyl-L-proline Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of trans-4-Cyclohexyl-L-proline
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a chiral catalyst in asymmetric synthesis to prepare chiral drug molecules with defined stereochemistry | Asymmetric hydrogenation, asymmetric Michael addition, etc. |
| Fine chemicals | Used to synthesize other organic compounds, particularly those requiring incorporation of cyclic structures or chiral centers | Chirality-directed synthesis, cyclization reactions, etc. |
| Biotechnology | Applied as a cofactor mimic in biocatalytic processes to facilitate specific enzymatic reactions | Enzymatic transformation, biocatalysis, etc. |
| Materials science | Employed in the synthesis of polymer materials with specialized properties, such as optical activity | Polymerization, copolymerization, etc. |
Manufacturing Quality Control of trans-4-Cyclohexyl-L-proline
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 210–220 nm, comparing peak area against a certified reference standard. |
| Chiral Purity (Enantiomeric Excess) | Chiral HPLC | Separation of enantiomers on a chiral stationary phase (e.g., Chiralpak AD-H), with UV detection; ee calculated from peak area ratio. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the stoichiometric reaction of iodine with water in pyridine/methanol medium. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection, quantifying common solvents (e.g., methanol, ethyl acetate) against calibration standards. |
| Heavy Metals (as Pb) | ICP-MS | Multi-element trace metal quantification after acid digestion, using isotopic dilution or external calibration for Pb and other toxic metals. |
| Residue on Ignition | Gravimetric Analysis | Mass loss measurement after high-temperature ashing (500–600 °C) to determine inorganic impurities. |
| Optical Rotation | [α]D | Measurement of specific rotation using a precision polarimeter at 20 °C with sodium D-line (589 nm) in specified solvent (e.g., 1 M HCl). |
| pH (1% w/v aqueous solution) | Potentiometric pH Measurement | Direct pH measurement using calibrated glass electrode in aqueous suspension after equilibration. |
| Related Substances | HPLC-UV (Forced Degradation Study) | Detection and quantification of structurally related impurities (e.g., cis-isomer, degradants) using gradient HPLC-UV under stressed conditions. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample via light scattering to determine D10, D50, D90 values per ISO 13320. |
| Microbial Limits | Membrane Filtration + Culture | Enumeration of aerobic microorganisms and absence testing for specified pathogens (e.g., E. coli, S. aureus) per USP <61> and <62>. |
Technical Specifications of trans-4-Cyclohexyl-L-proline
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 215–219 °C |
| Optical Rotation | -32.0 to -31.0 deg (c=1, in 1M HCl) |
| Identification (NMR) | Conforms to structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of trans-4-Cyclohexyl-L-proline
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of trans-4-Cyclohexyl-L-proline
Packaging of trans-4-Cyclohexyl-L-proline
Industrial trans-4-Cyclohexyl-L-proline Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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