China Factory Direct
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| CAS number | 1032452-86-0 |
| Product name | 3-(2-chloropyriMidin-4-yl)-1-Methylindole |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process Description |
|---|---|---|
| Pharmaceutical R&D | Intermediate for kinase inhibitors | Used as a key intermediate in the synthesis of targeted kinase inhibitors for anticancer drug development |
| Agrochemicals | Intermediate for fungicide synthesis | Applied as a structural building block in the synthesis of pyrimidine-based fungicides to enhance biological activity and selectivity |
| Fine chemicals | Organic synthesis reagent | Employed in the construction of indole derivatives and participates in modern organic transformations such as Suzuki coupling and Heck reactions |
| Biotechnology | Molecular probe development | Used to synthesize fluorescent or labeled derivatives for studying biomolecular interactions |
| Materials science | Functional material precursor | Applied in the design and synthesis of optoelectronic or organic semiconductor materials to impart specific electronic properties |
| Test Item | Common Analytical Methods | Method Overview |
|---|---|---|
| Identity | Proton Nuclear Magnetic Resonance (¹H NMR) | Confirm molecular structure through characteristic chemical shifts and coupling constants, especially signals from the indole ring, methyl, and chloropyrimidine moieties. |
| Infrared Spectroscopy (IR) | Detect characteristic absorption peaks of functional groups, such as C–Cl, C=N, N–CH₃, aromatic ring C–H, etc. | |
| Mass Spectrometry (MS, e.g., ESI-MS or EI-MS) | Confirm molecular ion peak ([M+H]⁺ or M⁺•) to verify that the molecular weight matches the theoretical value. | |
| Assay | High-Performance Liquid Chromatography (HPLC-UV) | Use a reversed-phase C18 column with a mobile phase of methanol/acetonitrile-water or buffer salt system; determine the content of the main component by external standard or area normalization method. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC-UV/DAD) | Establish a gradient elution program to separate and quantify process impurities and degradation products; impurity levels are typically reported as a percentage of the main peak area. |
| Residual Solvents | Gas Chromatography (GC-FID) | Head-space or direct injection to detect organic solvents possibly remaining from the synthesis process (e.g., dichloromethane, toluene, DMF, etc.). |
| Water Content | Karl Fischer Titration | Determine water content accurately using volumetric or coulometric methods, suitable for moisture-sensitive intermediates or active pharmaceutical ingredients (APIs). |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Oven Drying Method | Determine the total weight loss of volatile substances (including moisture and low-boiling solvents) by drying to constant weight at a specified temperature (e.g., 105°C). |
| Melting Point | Melting Point Apparatus | Determine the melting range using the capillary method or a digital melting point apparatus, used as an auxiliary indicator for purity and crystal form. |
| Elemental Analysis (Optional) | Elemental Analyzer (CHNS/O) | Determine the percentage content of elements such as C, H, N, Cl, and compare with theoretical values for structural confirmation of high-purity samples. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 148–152 °C |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.