N-BOC-ALPHA-METHYL-L-PROLINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 103336-06-7 |
| Product name | N-BOC-ALPHA-METHYL-L-PROLINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for N-BOC-ALPHA-METHYL-L-PROLINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk N-BOC-ALPHA-METHYL-L-PROLINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of N-BOC-ALPHA-METHYL-L-PROLINE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral intermediate for synthesizing angiotensin II receptor blockers (e.g., telmisartan) | Protected amino acid unit in peptide synthesis; incorporated into target molecules via solid-phase or solution-phase peptide synthesis |
| Biopharmaceutical R&D | Construction of biologically active peptides or peptidomimetics containing proline motifs | Boc-protected non-natural amino acid participating in coupling reactions (e.g., HATU/DIPEA-mediated amide bond formation) during organic synthesis |
| Chemical Synthesis | Chiral building block for asymmetric synthesis and heterocycle construction | After deprotection, participates in cyclization, alkylation, or other functional group transformations to construct complex molecular scaffolds |
Manufacturing Quality Control of N-BOC-ALPHA-METHYL-L-PROLINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification via reverse-phase HPLC with UV detection at 210 nm, using external standard calibration. |
| Chiral Purity | Chiral HPLC | Separation of enantiomers on a chiral stationary phase, comparing retention time and peak area ratio to reference standard. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents using gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the stoichiometric reaction of iodine with water in pyridine/methanol medium. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification by inductively coupled plasma mass spectrometry after acid digestion. |
| Residual Palladium | ICP-OES | Quantification of palladium impurity using inductively coupled plasma optical emission spectroscopy. |
| Loss on Drying | Gravimetric Analysis | Mass loss measured after heating under controlled temperature and vacuum to remove volatile components. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid phase transition temperature range using calibrated capillary apparatus. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral compound in solution. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities using gradient reverse-phase HPLC with UV detection. |
| Residual Chloride | Ion Chromatography | Separation and quantification of chloride anions using suppressed conductivity detection. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determination of hydrogen ion activity using calibrated glass electrode and pH meter. |
Technical Specifications of N-BOC-ALPHA-METHYL-L-PROLINE
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78-82°C |
| Optical Rotation | -51.0 to -49.0° (c=1, in methanol) |
| Identification (NMR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of N-BOC-ALPHA-METHYL-L-PROLINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of N-BOC-ALPHA-METHYL-L-PROLINE
Packaging of N-BOC-ALPHA-METHYL-L-PROLINE
Industrial N-BOC-ALPHA-METHYL-L-PROLINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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