China Factory Direct
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| CAS number | 103404-87-1 |
| Product name | 4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid hemisodium salt |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Biopharmaceuticals | Buffer for pH stabilization in protein purification, cell culture, and vaccine production | Used as a HEPES analog in chromatographic purification (e.g., ion exchange, gel filtration) and cell culture medium preparation to provide buffering capacity within pH 6.8–7.8 |
| Molecular Biology | Buffer component in nucleic acid electrophoresis and PCR reaction systems | Employed in native polyacrylamide gel electrophoresis (PAGE) and real-time quantitative PCR (qPCR) buffers to maintain enzyme activity and nucleic acid stability |
| In Vitro Diagnostics (IVD) | Buffer component in IVD reagent kits | Applied in immunoassays (e.g., ELISA) and clinical chemistry reagent kits to regulate reaction system pH, minimize interference from metal ions, and improve assay reproducibility |
| Cosmetics | Gentle pH adjuster for sensitive-skin care products | Substitutes conventional strong acids or bases in formulations such as soap-free cleansers and soothing serums to control system pH within the physiologically compatible range of 5.0–6.5 |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 210 nm, comparing peak area to a certified reference standard. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the reaction of water with iodine and sulfur dioxide in pyridine/methanol medium. |
| Residual Solvents | GC-FID | Separation and quantification of volatile organic solvents (e.g., ethanol, acetone) using gas chromatography with flame ionization detection. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element quantification via inductively coupled plasma mass spectrometry after acid digestion and dilution. |
| Sodium Content | ICP-OES | Quantitative determination of Na by measuring atomic emission intensity at characteristic wavelengths following sample dissolution. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride anions using anion-exchange column and suppressed conductivity detector. |
| Sulfate Impurity | Ion Chromatography | Separation and conductivity detection of sulfate anions using anion-exchange column and suppressed conductivity detector. |
| pH (1% w/v aqueous solution) | Potentiometric pH Measurement | Direct measurement using calibrated glass electrode in a standardized aqueous solution at 25 C. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against defined specifications under controlled lighting conditions. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range over which solid transitions to liquid, using calibrated capillary method. |
| Loss on Drying | Gravimetric Analysis | Mass loss measured after drying sample at 105 C for 2 hours under controlled atmospheric conditions. |
| Microbial Limits | Membrane Filtration and Plate Count | Enumeration of aerobic mesophilic microorganisms using membrane filtration followed by incubation on soybean-casein digest agar. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Melting Point | 245-250 °C |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.