Fmoc-N-methyl-D-valine Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 103478-58-6 |
| Product name | Fmoc-N-methyl-D-valine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for Fmoc-N-methyl-D-valine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Fmoc-N-methyl-D-valine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Fmoc-N-methyl-D-valine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a protecting amino acid monomer in peptide synthesis to construct peptide chains containing N-methylation modifications | Solid-phase or liquid-phase peptide synthesis (SPPS/LPPS); participates in coupling reactions after Fmoc deprotection |
| Biochemical Research | Employed to investigate the effects of N-methylated amino acids on peptide conformation, stability, and biological activity | Peptide fragment assembly and structure–function relationship analysis |
| Medicinal Chemistry | Serves as a key intermediate in synthesizing cyclic peptide drugs or protease inhibitors | Stepwise coupling and cyclization processes based on the Fmoc strategy |
Manufacturing Quality Control of Fmoc-N-methyl-D-valine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 268 nm based on peak area comparison to reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., Fmoc-D-valine, N-methyl-D-valine) using gradient HPLC and UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., DMF, DCM, methanol) by gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine-based redox reaction in anhydrous methanol medium. |
| Optical Purity (Enantiomeric Excess) | Chiral HPLC | Separates D- and L-enantiomers on a chiral stationary phase and calculates enantiomeric excess from peak area ratio. |
| Heavy Metals | ICP-OES | Quantifies elemental impurities (e.g., Pb, Cd, Ni, Cu) after acid digestion using inductively coupled plasma optical emission spectroscopy. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content by high-temperature incineration followed by precise weighing of residual residue. |
| pH (1% w/v aqueous solution) | Potentiometric Titration | Determines acidity/basicity of aqueous suspension using calibrated pH electrode and standardized acid/base titrant. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of visible particulates or discoloration under controlled white light against standard reference. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range at which solid transitions to liquid using capillary tube and calibrated heating block. |
| Loss on Drying | Thermogravimetric Analysis (TGA) | Determines volatile content by measuring mass loss upon controlled heating (e.g., 105 C, 2 h) under dry nitrogen atmosphere. |
| Elemental Analysis (C, H, N) | Combustion Analysis | Quantifies carbon, hydrogen, and nitrogen content by high-temperature combustion followed by gas chromatographic or thermal conductivity detection. |
Technical Specifications of Fmoc-N-methyl-D-valine
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | +65° to +71° (c=1, in DMF) |
| Melting Point | 128°C to 132°C |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of Fmoc-N-methyl-D-valine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Fmoc-N-methyl-D-valine
Packaging of Fmoc-N-methyl-D-valine
Industrial Fmoc-N-methyl-D-valine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply