China Factory Direct
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| CAS number | 103478-62-2 |
| Product name | Fmoc-N-methyl-L-leucine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of peptide therapeutics (e.g., antitumor peptides, antimicrobial peptides) | Amino acid protecting monomer for solid-phase peptide synthesis (SPPS) |
| Biochemistry | Peptide chain structural modification and research | Fmoc protecting group for stepwise coupling in solid-phase synthesis |
| Research | Preparation of non-natural amino acid derivatives | Chiral construction and protecting group manipulation in organic synthesis |
| Pharmaceutical R&D | Development of peptide-based vaccines and diagnostic reagents | Intermediate for assembly of target peptide sequences |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 268 nm. |
| Chiral Purity | Chiral HPLC | Separation of enantiomers on a chiral stationary phase; quantification of L-enantiomer excess relative to racemate or D-isomer. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., DMF, DCM, EtOAc) using flame ionization detection after headspace or direct injection. |
| Water Content | Karl Fischer Titration | Electrochemical titration with iodine-based reagent to determine trace water content based on stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) via inductively coupled plasma mass spectrometry after acid digestion. |
| Residual Palladium | ICP-OES | Quantification of palladium catalyst residues using inductively coupled plasma optical emission spectroscopy after microwave digestion. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled lighting and against white background. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, indicating crystallinity and purity. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light to confirm identity and enantiomeric integrity. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., Fmoc-Leu, N-methyl-L-leucine, dipeptide dimers) using gradient RP-HPLC. |
| Residue on Ignition | Gravimetric Analysis | Determination of inorganic ash content after high-temperature incineration and weighing of residual material. |
| pH of Solution | Potentiometric pH Measurement | Measurement of hydrogen ion activity in a defined aqueous or aqueous-organic solution using calibrated pH electrode. |
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 75-79°C |
| Optical Rotation | -15.0° to -19.0° (c=1, in DMF) |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.