(S)-CHROMAN-4-YLAMINE HYDROCHLORIDE Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 1035093-81-2 |
| Product name | (S)-CHROMAN-4-YLAMINE HYDROCHLORIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for (S)-CHROMAN-4-YLAMINE HYDROCHLORIDE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (S)-CHROMAN-4-YLAMINE HYDROCHLORIDE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (S)-CHROMAN-4-YLAMINE HYDROCHLORIDE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral intermediate for synthesizing optically active drug molecules (e.g., selective 5-HT1F receptor agonists as migraine treatment candidates) | Used in asymmetric synthesis or following chiral resolution, then subjected to amination and salt formation/purification; commonly serves as a chiral starting material for constructing the benzodihydropyran scaffold in multi-step organic syntheses, including coupling and cyclization reactions |
| Fine Chemicals | High-value chiral building block for developing novel chiral catalysts or ligands | Processed via derivatization reactions (e.g., acylation, sulfonylation, alkylation) to prepare chiral auxiliaries or precursors to phosphine/nitrogen ligands, applied in transition-metal-catalyzed asymmetric reactions |
Manufacturing Quality Control of (S)-CHROMAN-4-YLAMINE HYDROCHLORIDE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 220-280 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of structurally related impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3A/B. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., methanol, acetone, ethyl acetate) against calibrated standards. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine-based reagent to determine trace water content based on stoichiometric reaction with water. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As, Ni) after acid digestion, using inductively coupled plasma mass spectrometry for sub-ppb sensitivity. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using a silver indicator electrode to determine chloride ion concentration via precipitation endpoint detection. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific optical rotation using a polarimeter at 20 °C and sodium D-line (589 nm) to confirm chiral integrity and enantiomeric purity. |
| Residue on Ignition | Gravimetric Analysis | Ignition of sample at 700-800 °C followed by weighing of non-volatile inorganic residue to assess inorganic ash content. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using laser diffraction to determine D10, D50, D90 values per USP <429>. |
| Microbial Enumeration | Membrane Filtration | Quantitative recovery of aerobic microorganisms from solution via membrane filtration, followed by incubation on TSA and colony counting. |
| pH of Solution | Potentiometric pH Measurement | Direct measurement of aqueous suspension (1% w/v) using calibrated pH meter with glass electrode to verify acidity consistent with hydrochloride salt form. |
| Crystal Form | XRPD | Identification and verification of crystalline phase by comparison of diffraction pattern against reference standard using Cu-Ka radiation. |
Technical Specifications of (S)-CHROMAN-4-YLAMINE HYDROCHLORIDE
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.0% |
| Single Impurity | <=0.3% |
| Water Content (KF) | <=0.5% |
| Melting Point | 215–219 °C |
| Optical Rotation | +15.0 to +17.0 ° (c=1, in 1M HCl) |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of (S)-CHROMAN-4-YLAMINE HYDROCHLORIDE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (S)-CHROMAN-4-YLAMINE HYDROCHLORIDE
Safety Information of (S)-CHROMAN-4-YLAMINE HYDROCHLORIDE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (S)-CHROMAN-4-YLAMINE HYDROCHLORIDE
Industrial (S)-CHROMAN-4-YLAMINE HYDROCHLORIDE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply