China Factory Direct
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| CAS number | 10366-35-5 |
| Product name | 2-Chloronicotinamide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Insecticide intermediate | Used in the synthesis of nitrogen-containing heterocyclic insecticides |
| Pharmaceuticals | Pharmaceutical synthesis intermediate | Applied in the preparation of antiviral or antibacterial agents |
| Dyes | Dye intermediate | Used to synthesize dyes with specific molecular structures |
| Chemical Research | Laboratory reagent | Employed in amide formation reactions during organic synthesis |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination based on peak area comparison with a certified reference standard using reversed-phase chromatography and UV detection at ~220 nm. |
| Related Substances | HPLC-UV or HPLC-MS | Separation and quantification of structurally related impurities (e.g., 2-chloronicotinic acid, unreacted amide precursors) using gradient elution and UV or mass-selective detection. |
| Residual Solvents | GC-FID or GC-MS | Identification and quantification of volatile organic solvents (e.g., methanol, acetone, toluene) by gas chromatographic separation with flame ionization or mass spectrometric detection. |
| Heavy Metals (Total) | ICP-MS or AAS | Determination of toxic elements (e.g., Pb, Cd, Hg, As) after acid digestion, based on atomic emission or absorption signals proportional to elemental concentration. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration measuring water via stoichiometric reaction with iodine in pyridine/methanol medium. |
| Residue on Ignition | Gravimetric Analysis | Measurement of inorganic ash content after high-temperature incineration (500–600 °C) and weighing of residual non-volatile matter. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid-to-liquid phase transition occurs, indicating purity and identity consistency. |
| Chloride Ion Impurity | Ion Chromatography (IC) or Potentiometric Titration | Separation and quantification of free chloride ions (e.g., from hydrolysis) using anion-exchange chromatography or argentometric titration with AgNO₃. |
| pH of Aqueous Suspension | pH Meter | Measurement of hydrogen ion activity in a standardized suspension (e.g., 1% w/v in water), reflecting acidic/basic impurities or degradation products. |
| Particle Size Distribution | Laser Diffraction | Analysis of size distribution in dispersed powder sample via angular scattering pattern of laser light. |
| Bulk Density | ASTM D1895 (Method A) | Determination of mass per unit volume of freely settled powder in a calibrated cylinder. |
| Microbial Limits | Membrane Filtration & Culture | Enumeration of aerobic microorganisms, yeasts, and molds following filtration, membrane transfer to selective media, and incubation per pharmacopeial guidelines. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to confirm chiral integrity (if applicable; 2-chloronicotinamide is achiral, but method included for batch identity verification against reference). |
| Test Item | Specification |
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| Appearance | White solid |
| Purity | >=98.0% (by LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.