China Factory Direct
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| CAS number | 1036991-40-8 |
| Product name | 1,5-Dimethyl-1H-pyrazole-4-boronic acid,pinacol ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a key intermediate in the synthesis of kinase inhibitors, antitumor agents, and anti-inflammatory compounds | Carbon–carbon bond formation via Suzuki–Miyaura coupling to introduce pyrazole structural units |
| Agrochemicals | Used in the synthesis of novel bioactive pesticide molecules (e.g., fungicides, insecticides) | Palladium-catalyzed cross-coupling to construct heterocyclic compounds containing pyrazole scaffolds |
| Materials Science | Used to prepare organic optoelectronic materials (e.g., OLED emissive layer materials, organic semiconductors) | π-Conjugated system construction via Suzuki coupling to tune electronic properties of materials |
| Chemical Research | Used as a boronate-based synthon for building libraries of complex heterocyclic molecules | Multicomponent coupling, C–H activation, and subsequent functional group transformations |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~210–230 nm, comparing peak area against a certified reference standard. |
| Residual Solvents | GC-FID | Separation and quantification of volatile organic solvents (e.g., THF, toluene, methanol) using capillary GC with flame ionization detection against internal/external standards. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element quantification of trace metals after acid digestion, leveraging high sensitivity and isotopic resolution of inductively coupled plasma mass spectrometry. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration quantifying water via iodine generation and stoichiometric reaction with water in anhydrous methanol-based medium. |
| Residual Boronic Acid (Impurity) | HPLC-UV or LC-MS | Separation and quantification of unreacted 1,5-dimethyl-1H-pyrazole-4-boronic acid using reverse-phase chromatography with UV or mass-selective detection. |
| Chloride Ion | Ion Chromatography (IC) | Anion exchange separation followed by suppressed conductivity detection to quantify chloride as a common inorganic impurity from synthesis. |
| Appearance & Color | Visual Inspection / APHA Color Scale | Subjective assessment of physical state (crystalline solid) and color intensity compared to platinum-cobalt standard solutions. |
| Melting Point | Differential Scanning Calorimetry (DSC) | Thermal analysis measuring endothermic melting transition temperature and enthalpy to confirm identity and crystallinity. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or dispersed powder using light scattering principles to determine D10, D50, D90 values per ISO 13320. |
| Residual Palladium (if Pd-catalyzed synthesis) | ICP-OES | Quantification of palladium catalyst residue after microwave-assisted acid digestion using plasma optical emission spectroscopy. |
| Organic Volatile Impurities (e.g., Pinacol, Acetone) | GC-MS | Identification and quantification of volatile by-products or reagents using gas chromatography coupled with mass spectrometric detection. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light to assess chiral purity (though compound is achiral, used to detect chiral contaminants). |
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 118–122°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.