D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 103733-65-9 |
| Product name | D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeReagent GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
| Industry | Application | Process Description |
|---|---|---|
| Pharmaceuticals | Pharmaceutical Intermediates | Serves as a structural building block for synthesizing dopamine receptor agonists, neuroprotective agents, and other active pharmaceutical ingredients |
| Chemical Synthesis | Organic Synthesis Reagent | Used as a chiral auxiliary or catalyst in asymmetric synthesis |
| Research | Chemical Biology Research | Applied to study interactions between tetrahydroisoquinoline derivatives and neurotransmitter receptors |
| Materials Science | Functional Material Synthesis | Functions as a nitrogen-containing heterocyclic molecular module for designing and synthesizing novel functional materials |
Manufacturing Quality Control of D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 220 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities by gradient HPLC-UV, using relative response factors or external standards. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, ethyl acetate) by headspace GC with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine generated electrochemically in pyridine-free reagent. |
| Optical Rotation | [alpha]D Measurement | Measures specific optical rotation using a sodium D-line (589 nm) polarimeter to confirm chiral integrity and enantiomeric purity. |
| Heavy Metals | ICP-MS | Quantifies toxic elements (Pb, Cd, Hg, As) after acid digestion by inductively coupled plasma mass spectrometry with isotope dilution. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Sulfated Ash | Gravimetric Analysis | Determines inorganic residue after controlled combustion at 700-800 C, followed by precise weighing of the ash. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Measures hydrogen ion activity in a 1% w/v aqueous suspension using calibrated glass electrode and reference electrode. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry powder particle size by measuring angular scattering intensity of laser light through dispersed sample. |
| Microbial Contamination | Membrane Filtration | Detects aerobic microorganisms by filtration, membrane transfer to soybean-casein digest agar, and colony enumeration after incubation. |
| Residual Palladium | ICP-OES | Quantifies palladium catalyst residues after microwave-assisted acid digestion using inductively coupled plasma optical emission spectroscopy. |
Technical Specifications of D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 178~182°C |
| Optical Rotation | +161 to +167° (c=1, in 1M HCl) |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
Safety Information of D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
Industrial D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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