2-Bromo-4-cyanopyridine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 10386-27-3 |
| Product name | 2-Bromo-4-cyanopyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Bromo-4-cyanopyridine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Bromo-4-cyanopyridine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Bromo-4-cyanopyridine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for anticancer drugs and kinase inhibitors | Prepared via nucleophilic substitution of 4-cyanopyridine with a brominating reagent (e.g., NBS), for subsequent coupling or cyclization to synthesize active pharmaceutical ingredients (APIs) |
| Pesticides | Nitrogen-containing heterocyclic scaffold for synthesizing novel insecticides and fungicides | Serves as a key intermediate in nucleophilic substitution reactions with amines, alcohols, or thiols to construct pyridine-containing agrochemical active molecules |
| Chemical Synthesis | Multifunctional organic synthon incorporating both cyano and bromopyridyl groups | Functions as a bifunctional reagent: the bromo group enables Suzuki, Sonogashira, and other coupling reactions; the cyano group undergoes hydrolysis, reduction, or cycloaddition |
Manufacturing Quality Control of 2-Bromo-4-cyanopyridine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time relative to reference standards. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, acetone, DMF) against calibration curves. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generation to determine water content based on stoichiometric reaction with Karl Fischer reagent. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using isotopic mass spectrometry for high sensitivity. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column with conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Incineration at 700-800 C followed by weighing of residual inorganic ash after sulfuric acid treatment. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature using calibrated capillary apparatus per USP <741>. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion via light scattering to determine D10, D50, D90 values. |
| Bulk Density | ASTM D1895 | Measurement of mass per unit volume for freely settled powder using a calibrated cylinder and balance. |
| Organic Volatile Impurities (OVI) | GC-MS | Screening and semi-quantitative identification of unknown volatile impurities using mass spectral library matching. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Determination of pH in a defined water suspension (e.g., 1% w/v) using calibrated glass electrode and pH meter. |
Technical Specifications of 2-Bromo-4-cyanopyridine
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78-82°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Bromo-4-cyanopyridine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Bromo-4-cyanopyridine
Packaging of 2-Bromo-4-cyanopyridine
Industrial 2-Bromo-4-cyanopyridine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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