China Factory Direct
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| CAS number | 10405-02-4 |
| Product name | Trospium chloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for anticholinergic drugs | Used as a raw material in the synthesis of anticholinergic agents for treating conditions such as overactive bladder |
| Chemical Research | Organic synthesis reagent | Applied in laboratory-scale synthesis and structural studies of quaternary ammonium compounds |
| Detection Item | Common Testing Methods | Method Overview |
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| Identification Test | Infrared Spectroscopy (IR) | By measuring the infrared absorption spectrum of trospectam, comparison with a reference spectrum confirms characteristic functional groups and molecular structure. |
| Chemical Color Reaction | Utilizing the reaction of quaternary ammonium compounds with specific reagents (e.g., potassium iodobismuthate) to produce precipitates or color changes for preliminary identification. | |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Reverse-phase HPLC is used with a C18 column for separation, UV detection (typically at 210–220 nm), and quantification via external standard method to calculate the main component content. |
| Non-aqueous Titration | Titration of quaternary ammonium cations in non-aqueous solvents (e.g., glacial acetic acid) using perchloric acid as titrant and crystal violet as indicator to determine total alkalinity. | |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Gradient or isocratic HPLC is employed to separate and detect potential impurities such as synthetic intermediates and degradation products. Impurity levels are controlled by area normalization or the main component self-control method with correction factors. |
| pH Value | pH Meter Measurement | A solution of trospectam is prepared at a specified concentration (e.g., 1%), and the pH is directly measured using a calibrated pH meter to assess acidity/alkalinity in compliance with pharmacopeial requirements. |
| Drying Loss | Thermogravimetric Analysis (TGA) or Constant-temperature Drying at Atmospheric Pressure | The sample is dried at a specified temperature (e.g., 105°C) until constant weight is achieved, and the percentage loss in mass due to moisture or other volatile components is determined. |
| Residue on Ignition | Gravimetric Method | The sample is ignited at high temperature (approximately 700–800°C), and the residue of inorganic matter is weighed to control the total amount of inorganic impurities. |
| Chloride Content | Ion Chromatography (IC) or Silver Nitrate Titration (Volhard or Mohr Method) | Chloride ions are quantified using ion chromatography or silver nitrate titration (Volhard or Mohr method), verifying the composition of the ammonium chloride salt. |
| Solution Clarity and Color | Visual Turbidity/Color Comparison | The sample is dissolved at a defined concentration, and the resulting solution is visually compared with standard turbidity or color standards to check clarity and absence of abnormal discoloration. |
| Microbial Limits | Filtration Membrane Method or Plate Count Method | As per Chinese Pharmacopoeia or relevant regulations, tests are conducted for total aerobic bacteria count, total mold and yeast count, and control organisms (e.g., Escherichia coli), ensuring microbial contamination remains within acceptable limits. |
| Test Item | Specification |
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| Appearance | White Solid |
| Purity | >=98.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 192–196°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
| Optical Rotation | +15.0° to +17.0° (c=1, in 1M HCl) |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.