China Factory Direct
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| CAS number | 1041-01-6 |
| Product name | 3,5-Diiodo-L-thyronine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Pharmaceutical R&D | Used as a thyroid hormone analog to study thyroid function and related metabolic mechanisms | Biochemical analysis, receptor binding assays, cell culture models |
| Pharmaceutical Synthesis | Used as an intermediate or precursor in the synthesis of other thyroid hormone derivatives or radiolabeled probes | Organic synthesis, iodination reactions, protecting group strategies |
| Diagnostics Reagents | Used as a calibrator or competitive ligand in thyroid function assay kits | Immunoassays (e.g., RIA, ELISA), radiolabeling |
| Research Tools | Used as a selective T3/T4 receptor modulator to investigate nuclear receptor signaling pathways | Molecular biology experiments, gene expression regulation studies |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~225 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV/HRMS | Separation and identification of impurities (e.g., mono-iodinated analogs, des-iodo, or dehydro derivatives) via gradient HPLC coupled with UV and high-resolution mass spectrometry. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify residual solvents (e.g., methanol, acetone, ethyl acetate) per ICH Q3C guidelines. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic elements (Pb, Cd, Hg, As) after acid digestion, achieving sub-ppt detection limits. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration with iodine-based reagent to determine trace water content based on stoichiometric reaction with water. |
| Optical Rotation | [α]D | Polarimetric measurement at 589 nm (Na D-line) in sodium hydroxide solution to confirm chiral integrity and enantiomeric purity. |
| Residue on Ignition | Gravimetric Analysis | Ignition at 700–800 °C followed by weighing of inorganic residue to assess inorganic ash content per USP <281>. |
| Particle Size Distribution | Laser Diffraction | Dry dispersion and light scattering analysis to determine D10, D50, D90 values relevant for dissolution and formulation performance. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and absence testing for specified pathogens (e.g., E. coli, S. aureus) per USP <61> and <62>. |
| Test Item | Specification |
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| Appearance | Off white solid |
| ldentification(NMR) | Conforms to structure |
| Purity | ≥95.0% |
| Total of impurities | Maximum 1.00 percent |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.