GCLE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 104146-10-3 |
| Product name | GCLE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for GCLE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk GCLE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of GCLE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for cephalosporin antibiotics | Synthesis of third-generation cephalosporins such as ceftazidime |
| Pharmaceuticals | Preparation of antibacterial agents | Esterification or substitution reactions in chemical synthesis |
Manufacturing Quality Control of GCLE
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state, and presence of visible foreign particles under natural light or standard illumination. |
| Identification | Infrared Spectroscopy (IR) | Compare the sample spectrum with a reference spectrum to confirm consistency in major functional groups and molecular structural characteristics. |
| High-Performance Liquid Chromatography (HPLC) | Determine identity by comparing retention times with those of reference standards. | |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Use reversed-phase chromatographic columns (e.g., C18) and UV detector (typically at 254 nm), employing external standard or internal standard methods to quantify the main component. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Separate degradation products, by-products, and other impurities using gradient or isocratic elution; calculate peak areas for each impurity and report maximum individual impurity and total impurities. |
| Residual Solvents | Gas Chromatography (GC) | Detect organic solvents used during manufacturing (e.g., methanol, ethanol, dichloromethane, acetonitrile) according to ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Determine moisture content using either volumetric or coulometric Karl Fischer methods; suitable for moisture-sensitive cephalosporin compounds. |
| Melting Point | Melting Point Apparatus Method | Determine initial and final melting temperatures using automatic or manual melting point apparatus to assess purity and crystalline form consistency. |
| Specific Rotation | Polarimeter Method | Measure optical rotation of the solution at a specified wavelength (e.g., sodium D line, 589.3 nm) and temperature to evaluate optical purity. |
| Drying Loss | Thermogravimetric Analysis (TGA) or Oven Drying Method | Heat the sample at a specified temperature for a defined period and measure the percentage weight loss due to volatile substances. |
| Residue on Ignition | Sulfate Ash Method | Charring the sample at high temperature and weighing the residual inorganic matter to assess inorganic impurity levels. |
| Heavy Metals | Sulfide Colorimetry (e.g., Chinese Pharmacopoeia Method) | After sample digestion, react with sodium sulfide to form colored precipitates and perform colorimetric determination of total heavy metals such as lead. |
| Microbial Limits | Microbial Counting and Control Organism Tests | Perform total aerobic bacteria, mold, and yeast counts, and test for control organisms including Escherichia coli and Salmonella per pharmacopoeial requirements. |
Technical Specifications of GCLE
| Test Item | Specification |
|---|---|
| Appearance | White to orange to green powder or crystals |
| Purity | >=98.0% (by NMR) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 135–142°C |
| Optical Rotation | -25° to -35° (c=1, in methanol) |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of GCLE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of GCLE
Packaging of GCLE
Industrial GCLE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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