China Factory Direct
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| CAS number | 104197-13-9 |
| Product name | 4-BROMO-2,6-DIFLUOROPHENOL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate in the synthesis of anticancer agents (e.g., BTK inhibitors) | Nucleophilic aromatic substitution on brominated arenes to construct fluorinated phenoxy structures |
| Agrochemical Intermediates | Preparation of novel fluorinated insecticides and fungicides (e.g., trifluoromethyl aniline derivatives) | Ullmann coupling or copper-catalyzed amination with amine compounds |
| Organic Synthesis | Multifunctional arene building block for liquid crystal monomer synthesis | Generation of aryllithium reagents via halogen–metal exchange (e.g., n-BuLi), followed by addition to aldehydes/ketones or reaction with CO₂ to produce carboxylic acids |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 220-280 nm based on peak area comparison to reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities (e.g., isomers, bromination by-products) using gradient HPLC with UV detection and relative response factors. |
| Residual Solvents | GC-FID | Separates and quantifies volatile organic solvents (e.g., dichloromethane, toluene) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine generated electrochemically in pyridine-methanol medium. |
| Heavy Metals | ICP-OES | Measures total heavy metal content (Pb, Cd, Hg, As, etc.) after acid digestion by optical emission spectroscopy at element-specific wavelengths. |
| Chloride Impurity | Ion Chromatography | Quantifies chloride ions using suppressed conductivity detection after separation on an anion-exchange column with carbonate eluent. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary tube under controlled heating rate. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of visible particles or discoloration against white background under controlled lighting. |
| Acid Value | Acid-Base Titration | Measures acidic impurities by titration with standardized NaOH solution using phenolphthalein indicator or potentiometric endpoint. |
| Residue on Ignition | Gravimetric Analysis | Determines inorganic ash content by incinerating sample at 700-800 C and weighing residual non-volatile matter. |
| Bulk Density | Tap Density Measurement | Calculates mass per unit volume of freely poured powder, then after standardized tapping, to assess flow and packing behavior. |
| Particle Size Distribution | Laser Diffraction | Measures size distribution of solid particles in suspension by analyzing angular variation of laser light scattering intensity. |
| Test Item | Specification |
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| Appearance | White to off-white solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 64.0–67.0°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.