China Factory Direct
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| CAS number | 104199-82-8 |
| Product name | BOC-D-ASN-ONP |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Pharmaceutical R&D | Side-chain protecting reagent for aspartic acid residues in peptide synthesis | Used in solid-phase peptide synthesis (SPPS) to selectively protect the β-carboxyl group of aspartic acid, preventing branching during chain elongation; the Boc group is subsequently removed with TFA, while the p-nitrophenyl ester moiety is cleaved under mild basic conditions (e.g., piperidine/DMF) or via hydrogenolysis |
| Organic Synthesis | Chiral building block for amino acid derivatives | Serves as a chiral precursor of D-aspartic acid for condensation reactions to prepare cyclic peptides, glycopeptide antibiotics, or protease inhibitor intermediates; commonly employed with coupling reagents such as HATU and DIPEA |
| Biochemical Research | Site-specific protein modification and probe labeling | Enables introduction of a p-nitrophenol-containing modification at specific aspartic acid sites, facilitating subsequent conjugation of fluorescent dyes (e.g., aminofluorescein via nucleophilic substitution) or biotinylation reagents |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities relative to the main peak using gradient elution and UV detection. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents based on retention time and peak area. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generation in pyridine-methanol medium to determine trace water content. |
| Heavy Metals | ICP-OES | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion and plasma excitation emission measurement. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride anions using suppressed conductivity detection after aqueous extraction. |
| Residual Palladium | ICP-MS | Ultra-trace quantification of palladium catalyst residue following microwave-assisted digestion and mass spectrometric detection. |
| Optical Rotation | [alpha]D Measurement | Determination of specific rotation using a digital polarimeter at 20 degC with sodium D-line (589 nm) light source. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition determination by observing solid-to-liquid phase change in a capillary tube under controlled heating rate. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder size distribution based on angular scattering intensity of laser light passing through dispersed particles. |
| pH of Aqueous Suspension | pH Meter | Measurement of hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated glass electrode. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic mesophilic microorganisms and detection of specified pathogens after filtration and culture on selective media. |
| Test Item | Specification |
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| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128°C to 132°C |
| Optical Rotation | -15.0° to -19.0° (c=1, in DMF) |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.