2-Chloromandelic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 10421-85-9 |
| Product name | 2-Chloromandelic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Chloromandelic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Chloromandelic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Chloromandelic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key chiral intermediate for the synthesis of the anti-thrombotic drug clopidogrel | Optically pure o-chloromandelic acid is prepared via asymmetric synthesis or chiral resolution, followed by multi-step reactions to construct the clopidogrel molecular scaffold |
| Pharmaceuticals | Used in the synthesis of other cardiovascular drugs and biologically active chlorinated aromatic compounds | Employed as a chiral building block in organic synthesis reactions such as esterification and condensation |
| Agrochemicals | Predecessor for certain chiral pesticide intermediates | Incorporated into the target pesticide molecular structure via functional group transformation |
| Fine Chemicals | Used as a chiral auxiliary or ligand in asymmetric catalysis | Leverages its chiral hydroxyl and carboxyl groups for metal coordination or induction of an asymmetric environment |
Manufacturing Quality Control of 2-Chloromandelic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Acid-Base Titration with NaOH | Quantifies carboxylic acid group via neutralization with standardized sodium hydroxide solution using phenolphthalein or potentiometric endpoint detection. |
| Chlorine Content | Oxygen Flask Combustion followed by Ion Chromatography (IC) | Organic chlorine is converted to chloride ion by combustion in oxygen, then quantified by IC using conductivity detection. |
| Residual Solvents | Gas Chromatography (GC) with FID | Volatile organic solvents are separated on a capillary column and detected by flame ionization detector based on carbon response. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Sample digested in acid matrix is nebulized into plasma; elemental isotopes are detected by mass spectrometry for ultra-trace quantification. |
| Water Content | Karl Fischer Titration | Iodine reacts stoichiometrically with water in methanol-based reagent; endpoint detected electrometrically or photometrically. |
| Related Substances | HPLC with UV Detection | Impurities and degradation products are separated on reversed-phase C18 column and quantified by UV absorbance at 254 nm. |
| Melting Point | Capillary Melting Point Apparatus | Solid sample is heated gradually in capillary tube; temperature range at which solid-to-liquid phase transition occurs is recorded. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light caused by chiral centers in solution, indicating enantiomeric purity and identity. |
| Residue on Ignition | Gravimetric Analysis | Inorganic ash content determined by weighing residue after high-temperature incineration at 700-800 C. |
| Particle Size Distribution | Laser Diffraction | Particles dispersed in liquid medium scatter laser light; size distribution calculated from angular scattering intensity pattern. |
| pH of Aqueous Suspension | pH Meter Measurement | pH electrode measures hydrogen ion activity in saturated aqueous suspension of the compound. |
| Organic Volatile Impurities (e.g., benzene, chloroform) | Headspace GC-MS | Volatile impurities partitioned into headspace above sample solution are injected and identified/quantified by mass spectrometry. |
Technical Specifications of 2-Chloromandelic acid
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 124-128°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Chloromandelic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Chloromandelic acid
Packaging of 2-Chloromandelic acid
Industrial 2-Chloromandelic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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