(S)-3-Boc-Amino-gamma-butyrolactone Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 104227-71-6 |
| Product name | (S)-3-Boc-Amino-gamma-butyrolactone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (S)-3-Boc-Amino-gamma-butyrolactone
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (S)-3-Boc-Amino-gamma-butyrolactone Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (S)-3-Boc-Amino-gamma-butyrolactone
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral intermediate for synthesizing γ-aminobutyric acid (GABA) receptor modulators and neuroactive drugs (e.g., antiepileptic and anxiolytic candidates) | Key chiral building block for constructing the (S)-configured γ-butyrolactone ring in chiral resolution or asymmetric synthesis routes; incorporated into the target molecular scaffold following deprotection and functional group transformations |
| Organic Synthesis | Chiral synthon for constructing natural product analogues and functional molecules containing the (S)-γ-butyrolactone motif | Used as a substrate in Pd/Cu-catalyzed cross-coupling, nucleophilic ring-opening, or stereoselective reduction reactions—retaining the chiral center to enable subsequent stereocontrolled transformations |
Manufacturing Quality Control of (S)-3-Boc-Amino-gamma-butyrolactone
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 210 nm, comparing peak area to a certified reference standard. |
| Enantiomeric Purity | Chiral HPLC | Separates (R)- and (S)-enantiomers on a chiral stationary phase and calculates enantiomeric excess from peak areas. |
| Residual Solvents | GC-FID | Detects and quantifies volatile organic solvents (e.g., THF, ethyl acetate) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Measures trace water via coulometric or volumetric titration using iodine generation and stoichiometric reaction with water. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, Ni) after acid digestion using inductively coupled plasma mass spectrometry. |
| Residual Chloride | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and suppressed conductivity detection. |
| Related Substances | HPLC-UV | Identifies and quantifies structurally related impurities (e.g., hydrolysis or degradation products) using gradient HPLC-UV. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary apparatus per USP <741>. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light in solution to confirm chiral integrity and concentration-dependent optical activity. |
| Loss on Drying | Gravimetric Thermobalance | Determines volatile content by measuring mass loss after heating under controlled temperature and vacuum conditions. |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a standardized aqueous suspension (e.g., 1% w/v) using calibrated pH electrode. |
| Particle Size Distribution | Laser Diffraction | Analyzes size distribution of solid particles in suspension using Mie scattering theory and laser diffraction principles. |
Technical Specifications of (S)-3-Boc-Amino-gamma-butyrolactone
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 72.0–76.0 °C |
| Optical Rotation | -64.0 to -54.0 deg (c=1, in CHCl3) |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (S)-3-Boc-Amino-gamma-butyrolactone
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (S)-3-Boc-Amino-gamma-butyrolactone
Safety Information of (S)-3-Boc-Amino-gamma-butyrolactone
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (S)-3-Boc-Amino-gamma-butyrolactone
Industrial (S)-3-Boc-Amino-gamma-butyrolactone Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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