4-Aza-5a-androstan-1-ene-3-one-17b-carboxylic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 104239-97-6 |
| Product name | 4-Aza-5a-androstan-1-ene-3-one-17b-carboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Aza-5a-androstan-1-ene-3-one-17b-carboxylic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Aza-5a-androstan-1-ene-3-one-17b-carboxylic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Aza-5a-androstan-1-ene-3-one-17b-carboxylic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of steroid drugs | Used as an intermediate in the synthesis of androgens or related pharmaceuticals |
| Pesticides | Active ingredient or adjuvant in insecticides or herbicides | Applied in pesticide formulations as an active ingredient or adjuvant |
| Chemical manufacturing | Organic synthesis intermediate | Applied in synthetic reactions for other organic compounds |
Manufacturing Quality Control of 4-Aza-5a-androstan-1-ene-3-one-17b-carboxylic acid
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Chemical Purity | High-Performance Liquid Chromatography (HPLC) | Uses a C18 reversed-phase column with gradient elution of water-acetonitrile or methanol as mobile phase. Detection is performed using a UV detector (240–280 nm) to measure the main peak area for purity calculation. Suitable for quantification of the main component and impurity analysis. |
| Assay | HPLC-UV / HPLC-MS | Quantification using external or internal standard methods, with a calibration curve established from standard solutions of known concentration. MS detection enhances selectivity, especially in complex matrices. |
| Impurity Profile | HPLC-MS/MS or UPLC-QTOF-MS | Utilizes high-resolution mass spectrometry to identify structurally related impurities (e.g., decarboxylated products, oxidation products, isomers), enabling qualitative and semi-quantitative analysis in compliance with ICH Q3B guidelines. |
| Residual Solvents | Gas Chromatography (GC-FID / GC-MS) | According to ICH Q3C, detects organic solvents possibly remaining from manufacturing (e.g., methanol, acetonitrile, dichloromethane) using headspace or direct injection. |
| Water Content | Karl Fischer Titration (KF) | Electrochemical titration method to determine trace moisture in samples, ensuring compliance with pharmacopeial requirements for moisture control in pharmaceutical-grade materials (typically ≤5%). |
| Melting Point | Melting Point Apparatus | Determination of the melting point range of the pure substance as a physical constant for identification purposes. Typical steroid derivatives have melting points in the range of 180–230°C (must be verified experimentally). |
| Water Solubility / pH Value | Solubility Test + pH Meter | Measures solubility in water or buffer solutions and determines solution pH (expected to be weakly acidic due to carboxylic acid group, pH ≈ 4–6), providing guidance for formulation development. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (¹H-NMR, ¹³C-NMR) | Confirms molecular framework and functional group positions (e.g., C4 azacycle, C17 carboxylic acid) via proton and carbon NMR spectra. Comparison with theoretical structure serves as the "gold standard" for quality control. |
| Infrared Spectroscopy (IR) | Fourier Transform Infrared Spectroscopy (FT-IR) | Confirms functional groups and batch-to-batch consistency by characteristic absorption peaks (e.g., carboxylic acid C=O at 1710 cm⁻¹, N–H at 3300 cm⁻¹, C=N at 1650 cm⁻¹). |
| Heavy Metals and Inorganic Impurities | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Detects residual heavy metals such as lead, cadmium, mercury, and arsenic, in compliance with pharmacopeial limits (e.g., ICH Q3D). |
| Microbial Limits (if applicable) | Total Aerobic Microbial Count, Mold and Yeast Count, Test for Specified Pathogens | If used as raw material for oral or topical formulations, microbial contamination must be tested according to pharmacopeial methods (not mandatory for non-sterile materials). |
Technical Specifications of 4-Aza-5a-androstan-1-ene-3-one-17b-carboxylic acid
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178–182°C |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
| Optical Rotation | +12° to +16° (c=1, in methanol) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Aza-5a-androstan-1-ene-3-one-17b-carboxylic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Aza-5a-androstan-1-ene-3-one-17b-carboxylic acid
Safety Information of 4-Aza-5a-androstan-1-ene-3-one-17b-carboxylic acid
| Pictograms |   |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-Aza-5a-androstan-1-ene-3-one-17b-carboxylic acid
Industrial 4-Aza-5a-androstan-1-ene-3-one-17b-carboxylic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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