METHYLSULFAMOYL CHLORIDE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 10438-96-7 |
| Product name | METHYLSULFAMOYL CHLORIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for METHYLSULFAMOYL CHLORIDE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk METHYLSULFAMOYL CHLORIDE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of METHYLSULFAMOYL CHLORIDE
| Industry | Application | Process |
|---|---|---|
| Pesticides | Used as a herbicide intermediate in the synthesis of sulfonylurea herbicides (e.g., bensulfuron-methyl, pyrazosulfuron-ethyl) | Condensed with aromatic amines under alkaline conditions, followed by cyclization to form the sulfonylurea bridge |
| Pharmaceuticals | Used as an intermediate for antidiabetic drugs in the synthesis of sulfonylurea hypoglycemic agents (e.g., glibenclamide) | Reacted with substituted anilines to yield sulfonamides, then condensed with isocyanates or carbamates to form the urea linkage |
| Dyes | Used as a sulfonylating agent for reactive and acid dyes | Undergoes electrophilic substitution with dye intermediates containing amino or hydroxyl groups at low temperature to introduce the sulfonamide group |
Manufacturing Quality Control of METHYLSULFAMOYL CHLORIDE
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Utilizes a C18 column with water-acetonitrile or methanol-buffer salt mobile phase, detected by UV detector (210–254 nm). The main peak area is quantified using external standard or internal standard method. Suitable for stable derivatives or their salt forms. |
| Related Substances Testing | High-Performance Liquid Chromatography (HPLC) | Uses gradient elution to separate degradation products (e.g., methylsulfonylamide, chloride, oxidation products), with detection limits as low as 0.1%, complying with ICH Q3B guidelines. |
| Moisture Content | Karl Fischer Titration | Measures trace moisture using coulometric or volumetric Karl Fischer methods, suitable for moisture-sensitive chlorides to avoid hydrolysis interference. |
| Residual Solvents | Gas Chromatography (GC) | Employs headspace or direct injection with DB-624 or HP-INNOWAX columns and FID detection to analyze common solvent residues such as ethanol, acetone, dichloromethane, meeting ICH Q3C standards. |
| Chlorine Content | Ion Chromatography (IC) or Potentiometric Titration | After sample hydrolysis, released chloride ions are quantified via ion chromatography or AgNO₃ potentiometric titration to confirm the presence and ratio of chlorine atoms. |
| Melting Point / Thermal Stability | Differential Scanning Calorimetry (DSC) | Assesses melting behavior and decomposition temperature to evaluate thermal stability; detects possible decomposition or isomerization (e.g., methylsulfonylamide chloride is prone to decomposition). |
| Gas Chromatography-Mass Spectrometry (GC-MS) | GC-MS | Used for structural identification of unknown impurities, particularly effective for volatile by-products or degradation compounds, providing molecular ion and fragmentation information. |
| Nitrogen Content Determination | Kjeldahl Method or Elemental Analysis (EA) | Determines total nitrogen content via combustion analysis, verifying whether the nitrogen content matches theoretical values to support structural confirmation. |
| pH (in Solution State) | pH Meter Measurement | If in water-soluble salt form (e.g., methylsulfonylamide chloride hydrochloride), the pH of the aqueous solution is measured to assess acidity/alkalinity and degree of hydrolysis. |
| Appearance and Color | Visual Inspection + Spectrophotometry | Observes solid color (should be white to pale yellow crystalline); UV-Vis spectroscopy may be used at 400–700 nm to control colored impurities if necessary. |
Technical Specifications of METHYLSULFAMOYL CHLORIDE
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Odor | Characteristic odor |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of METHYLSULFAMOYL CHLORIDE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of METHYLSULFAMOYL CHLORIDE
Packaging of METHYLSULFAMOYL CHLORIDE
Industrial METHYLSULFAMOYL CHLORIDE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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