2-Fluoro-5-hydroxybenzenecarbonitrile Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 104798-53-0 |
| Product name | 2-Fluoro-5-hydroxybenzenecarbonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Fluoro-5-hydroxybenzenecarbonitrile
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Fluoro-5-hydroxybenzenecarbonitrile Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Fluoro-5-hydroxybenzenecarbonitrile
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate in the synthesis of anticancer agents (e.g., EGFR inhibitors) | Prepared via multi-step reactions including nitration, fluorination, hydrolysis, diazotization, and cyanation |
| Agrochemical Intermediates | Used in the synthesis of fluorinated benzamide-based insecticides and fungicides | Serves as a starting material for constructing fluorinated aromatic ring systems, participating in coupling or nucleophilic substitution reactions |
| Organic Synthesis | Production of fluorinated functional materials and liquid crystal monomers | Undergoes palladium-catalyzed cross-coupling (e.g., Suzuki, Heck reactions) to introduce additional functional groups and construct complex fluorinated aromatic frameworks |
Manufacturing Quality Control of 2-Fluoro-5-hydroxybenzenecarbonitrile
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 220-254 nm based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., isomers, hydrolysis/degradation products) using gradient HPLC-UV with suitable column and mobile phase. |
| Residual Solvents | GC-FID | Identifies and quantifies volatile organic solvents (e.g., acetonitrile, toluene, DMF) by gas chromatography with flame ionization detection using headspace or direct injection. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine generation in pyridine-free reagent system based on stoichiometric reaction with water. |
| Heavy Metals | ICP-OES | Measures total elemental impurities (e.g., Pb, Cd, Ni, Cu) after acid digestion by optical emission spectroscopy detecting characteristic atomic emission lines. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column with conductivity detection after sample dissolution and filtration. |
| Sulfate Impurity | Ion Chromatography | Separates and quantifies sulfate ions using anion-exchange column with conductivity detection following sample preparation. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing (700-800 C) and weighing of the remaining solids. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary tube method per USP/Ph. Eur. guidelines. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of visible particles or discoloration against specified criteria under controlled lighting conditions. |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode after equilibration. |
| Particle Size Distribution | Laser Diffraction | Determines size distribution of solid particles in suspension using angular scattering pattern analysis of laser beam passing through dispersed sample. |
Technical Specifications of 2-Fluoro-5-hydroxybenzenecarbonitrile
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 112–116°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Fluoro-5-hydroxybenzenecarbonitrile
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Fluoro-5-hydroxybenzenecarbonitrile
Safety Information of 2-Fluoro-5-hydroxybenzenecarbonitrile
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 2-Fluoro-5-hydroxybenzenecarbonitrile
Industrial 2-Fluoro-5-hydroxybenzenecarbonitrile Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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