4-CHLORO-3-HYDROXY BUTYRONITRILE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 105-33-9 |
| Product name | 4-CHLORO-3-HYDROXY BUTYRONITRILE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-CHLORO-3-HYDROXY BUTYRONITRILE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-CHLORO-3-HYDROXY BUTYRONITRILE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-CHLORO-3-HYDROXY BUTYRONITRILE
| Industry | Application | Process |
|---|---|---|
| Pesticides | Synthesis of insecticidal intermediates | Used as a key intermediate in the synthesis of synthetic pyrethroid insecticides such as cypermethrin, enabling preparation of high-efficacy, low-toxicity insecticides via condensation and cyclization reactions |
| Chemical Manufacturing | Organic synthesis intermediate | Applied in the synthesis of β-lactam antibiotic side chains and other fine chemicals, participating in nucleophilic substitution and reduction reactions |
| Pharmaceuticals | Drug synthesis precursor | Employed as a chloro- and hydroxy-functionalized building block for constructing specific drug molecule frameworks, particularly in anti-infective and central nervous system drug development |
Manufacturing Quality Control of 4-CHLORO-3-HYDROXY BUTYRONITRILE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantitative determination based on peak area comparison against a certified reference standard using a non-polar capillary column. |
| Water Content | Karl Fischer Titration (Coulometric mode) | Electrochemical titration where iodine generated in situ reacts stoichiometrically with water in the sample. |
| Residual Solvents (e.g., Acetonitrile, THF) | Gas Chromatography (GC) with FID or MS detection | Separation and quantification of volatile organic impurities using headspace or direct injection GC. |
| Heavy Metals (as Pb) | Atomic Absorption Spectroscopy (AAS) after acid digestion | Quantification of total heavy metals by measuring absorbance of ground-state atoms in flame or graphite furnace. |
| Chloride Ion Impurity | Potentiometric Titration with AgNO3 | Titration based on formation of AgCl precipitate, detected by silver ion-selective electrode potential change. |
| Acidity (as HCl) | Acid-Base Titration with NaOH and phenolphthalein indicator | Neutralization of acidic impurities using standardized sodium hydroxide solution to a visual endpoint. |
| Color (APHA) | Visual Comparison or Spectrophotometric Measurement at 455 nm | Comparison of sample color intensity against platinum-cobalt standard solutions or absorbance measurement at specified wavelength. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light caused by chiral compounds in solution at specified concentration and path length. |
| Residue on Ignition | Gravimetric Analysis after High-Temperature Ashing | Determination of inorganic residue mass remaining after incineration at 700-800 C in a muffle furnace. |
| Related Substances (Impurity Profile) | High-Performance Liquid Chromatography (HPLC) with UV detection | Separation and quantification of structurally related impurities using reversed-phase C18 column and UV absorbance detection. |
| Density | Digital Density Meter (Oscillating U-tube principle) | Measurement of sample density based on resonant frequency shift of a vibrating U-shaped tube filled with the liquid. |
| Refractive Index | Refractometry (Abbe type) | Determination of refractive index by measuring critical angle of total internal reflection at prism-sample interface. |
Technical Specifications of 4-CHLORO-3-HYDROXY BUTYRONITRILE
| Test Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Refractive Index (n20/D) | 1.435–1.445 |
| Relative Density (20°C/25°C) | 1.210–1.230 g/cm³ |
| Odor | Characteristic pungent odor |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-CHLORO-3-HYDROXY BUTYRONITRILE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Safety Information of 4-CHLORO-3-HYDROXY BUTYRONITRILE
| Pictograms |   |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 4-CHLORO-3-HYDROXY BUTYRONITRILE
Industrial 4-CHLORO-3-HYDROXY BUTYRONITRILE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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