China Factory Direct
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| CAS number | 105140-25-8 |
| Product name | 3-[N-Tris(hydroxymethyl)methylamino]-2-hydroxypropanesulfonic acid sodium salt |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Electroplating | Complexing and buffering agent for cyanide-free copper electroplating | Used in alkaline cyanide-free copper plating electrolytes to maintain stable pH (pH 10–12), improving deposit uniformity and adhesion |
| Electroplating | Copper plating additive for through-hole metallization in printed circuit boards (PCBs) | Acts as the primary complexing agent, forming stable, soluble complexes with copper ions to enable uniform filling of high-aspect-ratio vias |
| Electroplating | Environmentally compatible ligand alternative in electronic plating | Replaces cyanide-containing or strongly chelating amines (e.g., EDTA), reducing wastewater treatment complexity and complying with RoHS and REACH requirements |
| Biochemistry | Component of protein crystallization buffers | Leverages its broad buffering range (pH 7.5–9.5) and low interference with metal ion chelation to stabilize crystal growth conditions |
| Pharmaceutical Intermediates | Investigation as a drug carrier or sustained-release excipient | In laboratory-scale development, exploring the potential of its sodium sulfonate and hydroxyl groups to jointly enhance water solubility and biocompatibility |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by reverse-phase HPLC with UV detection at 205 nm, using external standard calibration. |
| Water Content | Karl Fischer Titration | Electrochemical titration with iodine reagent to determine water based on stoichiometric reaction. |
| pH (1% aqueous solution) | Potentiometric pH Measurement | Measurement of hydrogen ion activity using calibrated glass electrode in aqueous solution. |
| Sodium Content | Flame Photometry | Quantification of Na+ emission intensity at 589 nm upon atomization in air-acetylene flame. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element detection of trace metals via atomic emission after acid digestion and plasma excitation. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of Cl- using anion-exchange column with conductivity detection. |
| Residue on Ignition | Gravimetric Analysis | Mass loss measurement after high-temperature ashing to determine inorganic non-volatile residue. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities using gradient HPLC with UV detection. |
| Sulfonate Content | Ion Chromatography | Quantification of sulfonate group via indirect conductivity detection after anion separation. |
| Free Formaldehyde | Acetylacetone Spectrophotometry | Derivatization with acetylacetone under acid heating to form yellow chromophore measured at 412 nm. |
| Appearance (Solution Clarity) | Visual Inspection | Assessment of clarity and absence of visible particles in a 1% aqueous solution against standard reference. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms after filtration, membrane transfer, and incubation on soybean-casein digest agar. |
| Test Item | Specification |
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| Appearance | White solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
| Identification (NMR) | Consistent with structure |
| Odor | Characteristic, mild |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.