METHYL 3-(CYCLOPROPYLAMINO)-2-(2,4-DICHLORO-5-FLUOROBENZOYL)ACRYLATE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 105392-26-5 |
| Product name | METHYL 3-(CYCLOPROPYLAMINO)-2-(2,4-DICHLORO-5-FLUOROBENZOYL)ACRYLATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 105392-26-5
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 105392-26-5 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 105392-26-5
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for synthesizing quinolone antibacterial agents (e.g., fluoroquinolone antibiotics) | Used in organic synthesis and condensation reactions |
| Agrochemicals | Intermediate for preparing high-efficiency, broad-spectrum fungicides or insecticides | Applied in acylation and cyclopropylamination reactions |
| Fine Chemicals | Raw material for synthesizing fluorinated and chlorinated heterocyclic compounds | Employed in catalytic reactions and solvent extraction |
| Research | Intermediate for drug molecule structural modification or biological activity studies | Used in laboratory-scale synthesis |
Manufacturing Quality Control of 105392-26-5
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC with UV detection; identification based on retention time relative to reference standards. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., methanol, dichloromethane) based on calibrated response factors. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generation in pyridine-free reagent; water reacts stoichiometrically with iodine and sulfur dioxide in methanol medium. |
| Heavy Metals | ICP-MS | Quantitative determination of elemental impurities (e.g., Pb, Cd, As, Hg) after acid digestion, using mass spectrometry for high sensitivity and multi-element capability. |
| Chloride Content | Ion Chromatography | Separation and conductivity detection of chloride ions after sample dissolution and filtration; quantified via external calibration curve. |
| Residual Palladium | ICP-OES | Determination of palladium residue from catalytic hydrogenation steps after microwave-assisted acid digestion and plasma optical emission detection. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific rotation using a polarimeter at 20 C and sodium D-line (589 nm) to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed as the temperature range over which solid-to-liquid phase change occurs, indicating crystallinity and absence of significant impurities. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample using Mie scattering theory to determine volume-based particle size distribution. |
| pH of Aqueous Slurry | Potentiometric pH Measurement | Electrode-based measurement of hydrogen ion activity in a defined suspension (e.g., 10% w/v in water) to assess acidic/basic surface impurities. |
| Organic Volatile Impurities (OVI) | GC-MS | Identification and quantification of low-level volatile organic impurities using gas chromatography coupled with mass spectrometric detection and library matching. |
Technical Specifications of 105392-26-5
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.5% (by HPLC) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142–146°C |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 105392-26-5
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 105392-26-5
Packaging of 105392-26-5
Industrial 105392-26-5 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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