Benzoic acid, 2-broMo-5-fluoro-3-nitro- Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1055331-73-1 |
| Product name | Benzoic acid, 2-broMo-5-fluoro-3-nitro- |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Benzoic acid, 2-broMo-5-fluoro-3-nitro-
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Benzoic acid, 2-broMo-5-fluoro-3-nitro- Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Benzoic acid, 2-broMo-5-fluoro-3-nitro-
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate for synthesizing active pharmaceutical ingredients (APIs), including antitumor agents and kinase inhibitors | Undergoes nucleophilic substitution with amines in inert solvents (e.g., DMF or THF), or multi-step transformations—including reduction and cyclization—to construct heterocyclic scaffolds |
| Pesticide Development | Structural building block for developing novel fluorinated nitrobenzene-based insecticides or herbicides | Serves as a starting material in coupling reactions (e.g., Suzuki, Heck) to introduce specific substituents and optimize biological activity |
| Organic Synthesis | Multifunctional aromatic building block offering orthogonal reactivity of bromo, fluoro, nitro, and carboxylic acid functional groups | Bromo group enables metal-catalyzed cross-coupling; nitro group undergoes selective reduction to amino; carboxylic acid is converted to acyl chloride, ester, or amide; fluoro group remains intact to modulate molecular polarity and metabolic stability |
Manufacturing Quality Control of Benzoic acid, 2-broMo-5-fluoro-3-nitro-
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification via retention time matching and threshold-based reporting. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, ethyl acetate, toluene) based on calibrated response factors. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generation in pyridine-free reagent to determine water by stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element detection after acid digestion; quantifies metals (e.g., Pb, Cd, Ni, Fe) at sub-ppb levels using isotopic mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separation of anions on a high-capacity anion-exchange column with suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Ignition at 700-750 C followed by weighing of non-volatile residue after sulfuric acid treatment. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature range using calibrated capillary method per USP <741>. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion via light scattering to obtain D10, D50, D90 values per ISO 13320. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light source in solution at specified concentration and temperature. |
| Residual Palladium | ICP-OES | Quantification after microwave-assisted acid digestion using plasma optical emission spectroscopy at element-specific wavelengths. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Direct measurement using calibrated glass electrode in a defined suspension (e.g., 1% w/v in water). |
Technical Specifications of Benzoic acid, 2-broMo-5-fluoro-3-nitro-
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 152–156 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Benzoic acid, 2-broMo-5-fluoro-3-nitro-
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Benzoic acid, 2-broMo-5-fluoro-3-nitro-
Safety Information of Benzoic acid, 2-broMo-5-fluoro-3-nitro-
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Benzoic acid, 2-broMo-5-fluoro-3-nitro-
Industrial Benzoic acid, 2-broMo-5-fluoro-3-nitro- Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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