1-CBZ-2-HYDROXYMETHYL-PIPERIDINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 105706-75-0 |
| Product name | 1-CBZ-2-HYDROXYMETHYL-PIPERIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-CBZ-2-HYDROXYMETHYL-PIPERIDINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-CBZ-2-HYDROXYMETHYL-PIPERIDINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-CBZ-2-HYDROXYMETHYL-PIPERIDINE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key chiral intermediates for synthesizing antiviral, anticancer, and central nervous system drugs | Introducing the piperidine ring structure via reduction, condensation, or coupling reactions to construct complex molecular frameworks |
| Organic Synthesis | Chiral building blocks for constructing nitrogen-containing heterocyclic compounds | Functional group transformations—such as oxidation, esterification, or alkylation of hydroxymethyl groups—under CBZ protection |
| Drug Discovery | Lead compound optimization for developing novel analgesics, antidepressants, or cognitive enhancers | Enhancing target selectivity and bioavailability through structural modification and structure–activity relationship (SAR) studies |
Manufacturing Quality Control of 1-CBZ-2-HYDROXYMETHYL-PIPERIDINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 210-230 nm based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient HPLC-UV; identification via retention time matching and threshold-based reporting. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, ethyl acetate) by gas chromatography with flame ionization detection using headspace sampling. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration using iodine generation in pyridine-free reagent system. |
| Heavy Metals | ICP-OES | Quantifies metals (e.g., Pb, Cd, Ni, Fe) after acid digestion using inductively coupled plasma optical emission spectrometry. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after controlled combustion at 700-800 C followed by precise weighing of ash. |
| Optical Rotation | Polarimetry | Determines specific rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range of solid-to-liquid transition using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of sample against standard white background under controlled lighting. |
| pH of Aqueous Solution | pH Meter | Measures hydrogen ion activity in a saturated aqueous suspension using calibrated glass electrode system. |
| Particle Size Distribution | Laser Diffraction | Determines size distribution of solid particles in suspension using Mie scattering theory and laser diffraction analysis. |
Technical Specifications of 1-CBZ-2-HYDROXYMETHYL-PIPERIDINE
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 82.0–86.0°C |
| Optical Rotation | -15.0° to -19.0° (c=1, in methanol) |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-CBZ-2-HYDROXYMETHYL-PIPERIDINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-CBZ-2-HYDROXYMETHYL-PIPERIDINE
Safety Information of 1-CBZ-2-HYDROXYMETHYL-PIPERIDINE
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 1-CBZ-2-HYDROXYMETHYL-PIPERIDINE
Industrial 1-CBZ-2-HYDROXYMETHYL-PIPERIDINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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