(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 105812-81-5 |
| Product name | (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 105812-81-5
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 105812-81-5 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 105812-81-5
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Potential drug intermediate | Used in the synthesis of biologically active compounds as precursors for new drug development |
| Chemical synthesis | Organic synthesis intermediate | Applied as a chiral building block in organic reactions, including catalytic asymmetric synthesis |
| Materials science | Functional materials research | Employed as a ligand or structural unit in the design and preparation of novel functional materials |
| Biochemistry | Enzyme inhibitor research | Investigated for the design and synthesis of inhibitors targeting specific enzymes |
| Agrochemical R&D | Derivative of agrochemical active ingredients | Used to develop insecticidal or fungicidal compounds as lead structures for agrochemical structural optimization |
Manufacturing Quality Control of 105812-81-5
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 220 nm, comparing peak area to a reference standard. |
| Chiral Purity | (S,S)- and (R,R)-Diastereomer Content | Chiral HPLC |
| Optical Rotation | Polarimetry | Measurement of the angle of rotation of plane-polarized light induced by the chiral compound in solution. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents per ICH Q3C. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the reaction of iodine with water in a controlled electrochemical cell. |
| Heavy Metals | ICP-MS | Inductively coupled plasma mass spectrometry for trace-level quantification of elements such as Pb, Cd, Hg, and As. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and conductivity detection. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities using gradient HPLC with UV detection. |
| Residual Palladium | ICP-OES | Inductively coupled plasma optical emission spectroscopy for quantification of palladium from catalytic hydrogenation steps. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determination of hydrogen ion activity using calibrated glass electrode and pH meter. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement via visual observation of solid-to-liquid phase change in a capillary tube. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against established reference standards under controlled lighting. |
Technical Specifications of 105812-81-5
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128–132°C |
| Optical Rotation | -39.0 to -36.0° (c=1, in methanol) |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 105812-81-5
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 105812-81-5
Packaging of 105812-81-5
Industrial 105812-81-5 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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