China Factory Direct
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| CAS number | 105827-91-6 |
| Product name | 2-Chloro-5-chloromethylthiazole |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Organic synthesis intermediate | Used in the synthesis of antifungal agents and other thiazole-containing pharmaceuticals |
| Pesticide Industry | Raw material for fungicide or herbicide synthesis | Chloromethyl group introduced via substitution reaction |
| Chemical Industry | Starting material for thiazole compound synthesis | Applied in constructing complex organic molecular frameworks |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Purity Analysis | High-Performance Liquid Chromatography (HPLC) | Utilizes a reverse-phase column (e.g., C18) with methanol/water or acetonitrile/water as the mobile phase. A UV detector at 230–260 nm wavelength is used for detection. It effectively separates and quantifies the main component and impurities, suitable for purity determination and content analysis. |
| Content Determination | Gas Chromatography (GC) | Suitable for volatile compounds. Uses a capillary column (e.g., DB-5MS) with helium as the carrier gas and a Flame Ionization Detector (FID). Sample derivatization or direct injection is required, suitable for high-precision quantification. |
| Impurity Analysis | Liquid Chromatography-Mass Spectrometry (LC-MS) | Combines the separation capability of HPLC with the qualitative and quantitative advantages of mass spectrometry. It can identify structurally similar impurities, byproducts, and degradation products, offering high sensitivity for trace impurity identification. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | ¹H NMR and ¹³C NMR provide molecular structure information, confirming the substitution position and structural integrity of the chloromethyl and thiazole ring. It is the gold standard for structural confirmation. |
| Molecular Weight Determination | Mass Spectrometry (MS) | Obtains molecular ion peaks via electrospray ionization (ESI-MS) or electron impact ionization (EI-MS), confirming the molecular weight (theoretical value approximately 179.54 g/mol), assisting in structural identification. |
| Residual Solvent Detection | Gas Chromatography (GC-FID/MS) | Used to detect residual organic solvents from the synthesis process (e.g., dichloromethane, acetonitrile, etc.). Headspace or direct injection methods are employed, complying with ICH Q3A/Q3C guidelines. |
| Thermal Stability Analysis | Thermogravimetric Analysis (TGA) | Evaluates weight loss behavior during heating to assess thermal stability and decomposition temperature, aiding in process development and storage condition design. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Melting Point | 82-86°C |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.