China Factory Direct
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| CAS number | 105931-73-5 |
| Product name | 1-BROMO-3-FLUORO-4-IODOBENZENE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Organic synthesis intermediate | Used to construct fluorinated aromatic compounds; participates in transition metal-catalyzed reactions such as Suzuki and Heck couplings to build drug molecule scaffolds |
| Materials Science | Liquid crystal material intermediate | Introduces halogenated aryl units into liquid crystal molecular structures to modulate dielectric anisotropy and phase transition temperature |
| Organic Synthesis | Polyhalogenated arene functionalization precursor | Enables selective cross-coupling via differential reactivity of bromine and iodine, facilitating multi-step functionalization of aromatic rings |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantitative determination based on peak area comparison against a certified reference standard using a non-polar capillary column. |
| Residual Solvents | Gas Chromatography (GC) with Headspace sampling | Volatile organic impurities are separated and quantified by headspace GC-FID or GC-MS against USP/ICH Q3C limits. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration where iodine generated in situ reacts stoichiometrically with water in the sample. |
| Heavy Metals | ICP-OES (Inductively Coupled Plasma Optical Emission Spectrometry) | Multi-element detection of metal impurities (e.g., Pb, Cd, Hg, As) after acid digestion and plasma excitation. |
| Acid-Base Impurities | Acid-Base Potentiometric Titration | Titration with standardized NaOH or HCl to detect acidic or basic impurities via pH inflection point. |
| Residual Inorganics (Sulfate, Chloride) | Ion Chromatography (IC) | Separation and quantification of anions using suppressed conductivity detection with eluent gradient. |
| Volatility Loss | Thermogravimetric Analysis (TGA) | Mass loss measured under controlled nitrogen atmosphere to assess thermal stability and volatile residue below 150 C. |
| Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light to confirm chiral purity (if applicable; compound is achiral but method verifies absence of chiral contaminants). |
| Appearance and Color | Visual Inspection and Hazen (APHA) Color Scale | Comparison of sample solution clarity and color intensity against platinum-cobalt standards in specified solvent. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature range using calibrated digital melting point instrument. |
| Residual Catalyst (Pd, Cu) | ICP-MS (Inductively Coupled Plasma Mass Spectrometry) | Ultra-trace detection of transition metal catalysts post-synthesis using high-resolution mass spectrometry. |
| Related Substances | HPLC with UV Detection | Separation and quantification of structurally related impurities using reversed-phase C18 column and gradient elution. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 45–49°C |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.