4-Bromothiophenol Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 106-53-6 |
| Product name | 4-Bromothiophenol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Bromothiophenol
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Bromothiophenol Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Bromothiophenol
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of antitumor drug intermediates (e.g., BRAF inhibitors) | Used in nucleophilic substitution or palladium-catalyzed cross-coupling reactions |
| Pesticides | Synthesis of insecticide and fungicide intermediates (e.g., benzothiazole-based agrochemicals) | Applied in cyclization or thioetherification reactions |
| Materials Science | Preparation of precursors for organic light-emitting diode (OLED) hole-transport materials | Employed in oxidative coupling or S-arylation reactions |
| Dyes | Synthesis of benzothiazole-based fluorescent brighteners and reactive dye intermediates | Utilized in cyclization reactions (condensation with α-halo carbonyl compounds) |
| Rubber Industry | Synthetic intermediate for rubber accelerators (e.g., TBBS) | Reacted with carbon disulfide and amines to produce thiazole-based accelerators |
Manufacturing Quality Control of 4-Bromothiophenol
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Purity Analysis | High-Performance Liquid Chromatography (HPLC) | Uses a reverse-phase chromatographic column and UV detector (e.g., 254 nm) to quantify the purity of the main component by retention time and peak area. Suitable for rapid, high-precision determination of organic impurities and the main content. |
| Content Determination | Gas Chromatography (GC) | Utilizes a capillary column and FID detector for quantification using internal or external standard methods. Applicable for volatile and thermally stable compounds; can simultaneously detect residual solvents. |
| Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Analyzes hydrogen/carbon atomic chemical shifts and coupling constants via ¹H NMR and ¹³C NMR to confirm molecular structure and substituent positions, ensuring correct synthesis of the target compound. |
| Impurity Identification | Liquid Chromatography-Mass Spectrometry (LC-MS) | HPLC separates the sample before mass spectrometry detection, allowing structural inference of unknown impurities through molecular ion peaks and fragment ions. Particularly suitable for qualitative analysis of trace organic impurities. |
| Moisture Content | Karl Fischer Titration Method | Accurately determines trace moisture content in samples using electrochemical titration, especially important for hygroscopic or water-sensitive compounds. |
| Heavy Metal Residues | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | A highly sensitive multi-element analytical technique capable of detecting multiple heavy metals such as lead, cadmium, mercury, and arsenic residues, complying with pharmacopoeia or environmental standards. |
| Melting Point Determination | Digital Melting Point Apparatus | Observes the temperature range from initial melting to complete melting under programmed heating to assess substance purity and crystallization state, a basic physical property quality indicator. |
| Appearance and Color | Visual Color Comparison / Colorimeter | Visually or instrumentally measures the color of the sample under standard lighting conditions and compares it to reference standards to evaluate any discoloration due to oxidation or impurities. |
| Residual Volatile Organic Solvents | Headspace Gas Chromatography (HS-GC) | The sample is heated, and the headspace gas is injected into GC-FID or GC-MS for detecting residual solvents (e.g., methanol, ethyl acetate), complying with ICH Q3C guidelines. |
| Thiol Group Activity Verification | Iodometric Method / Ellman's Reagent Method | Uses specific reactions between thiols and iodine or DTNB reagent to quantify free -SH groups via titration or absorbance change, verifying the integrity of functional groups. |
Technical Specifications of 4-Bromothiophenol
| Test Item | Specification |
|---|---|
| Appearance | White to orange crystalline powder |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 54.0–57.0°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Identification (NMR) | Conforms to reference standard |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Bromothiophenol
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Bromothiophenol
Packaging of 4-Bromothiophenol
Industrial 4-Bromothiophenol Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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