China Factory Direct
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| CAS number | 106268-96-6 |
| Product name | (2R)-(-)-2-METHYLGLYCIDYL 4-NITROBENZOATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key chiral intermediate for the synthesis of levofloxacin | Preparation of the C-2 side chain precursor for levofloxacin via chiral resolution or asymmetric synthesis, followed by acid chlorination and aminolysis to introduce the quinolone core |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Chiral Purity | Chiral HPLC | Enantiomeric excess assessment using a chiral stationary phase and UV detection, resolving (2R)-(-) enantiomer from (2S)-(+) form. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on iodine-sulfur dioxide reaction stoichiometry to quantify trace water. |
| Residual Solvents | GC-FID | Gas chromatographic separation followed by flame ionization detection, calibrated against USP/ICH Q3C limits. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion and isotopic detection. |
| Chloride Impurity | Ion Chromatography | Separation of anions on anion-exchange column with suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Ignition at 700-800 C followed by weighing of residual inorganic salts after sulfuric acid treatment. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement via controlled heating; sharpness and range indicate crystallinity and purity. |
| Optical Rotation | [alpha]D Measurement | Specific rotation determination at 589 nm using sodium D-line light in solution, confirming chiral identity and enantiomeric integrity. |
| Related Substances | HPLC-UV (Forced Degradation) | Stress testing (acid/base/oxidative/thermal/light) followed by HPLC-UV to identify and quantify degradants and process impurities. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersion using Mie theory to determine D10/D50/D90 values per USP <429>. |
| Microbial Limits | Membrane Filtration | Quantitative recovery of aerobic microorganisms and absence testing for specified pathogens per USP <61> and <62>. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Optical Rotation | -6.0 to -7.0 deg (c=1, in CHCl3) |
| Melting Point | 112.0 to 116.0 °C |
| Total Impurities | <=2.0% (GC-MS) |
| Single Impurity | <=0.5% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.