N-Boc-D-Phenylalaninol Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 106454-69-7 |
| Product name | N-Boc-D-Phenylalaninol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for N-Boc-D-Phenylalaninol
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk N-Boc-D-Phenylalaninol Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of N-Boc-D-Phenylalaninol
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral synthon for synthesizing antiviral agents (e.g., HIV protease inhibitors) and neuroactive compounds | Nucleophilic addition of N-Boc-protected D-phenylalaninol to carbonyl compounds to construct chiral amino alcohol-based drug intermediates |
| Pharmaceuticals | Optically pure intermediates for synthesizing β-blockers and antidepressants | Deprotection of N-Boc-D-phenylalaninol followed by acylation or alkylation to introduce pharmacophores |
| Chemical Reagents | Chiral auxiliary or ligand precursor for asymmetric catalysis | Coordination with metal catalysts (e.g., Ti, Cu) to generate a chiral environment for alkene hydrogenation or Diels–Alder reactions |
| Pharmaceuticals | Side-chain structure for synthesizing non-nucleoside reverse transcriptase inhibitors (NNRTIs) | Sulfonylation or phosphorylation of the hydroxyl group of N-Boc-D-phenylalaninol, followed by coupling to a heterocyclic core |
Manufacturing Quality Control of N-Boc-D-Phenylalaninol
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210-220 nm, comparing peak area to a certified reference standard. |
| Chiral Purity | Chiral HPLC | Enantiomeric excess assessment using a chiral stationary phase and UV detection, resolving D- and L-enantiomers based on differential retention. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration measuring water via iodine-sulfur dioxide reaction in anhydrous methanol/pyridine medium. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., THF, toluene, ethyl acetate) using gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-MS | Multi-element trace metal analysis (e.g., Pb, Cd, Hg, As) after acid digestion, based on mass-to-charge ratio detection. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and suppressed conductivity detection. |
| Sulfate Impurity | Ion Chromatography | Separation and quantification of sulfate ions using anion-exchange column and suppressed conductivity detection. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., N-Boc-D-phenylalanine, de-Boc product) using gradient reverse-phase HPLC. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement by observing solid-to-liquid phase change under controlled heating rate. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light, indicating enantiomeric identity and concentration. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of visible particulates or discoloration against established reference standards. |
| Loss on Drying | Gravimetric Analysis | Mass loss determination after drying under specified temperature/vacuum conditions, reflecting volatile content including residual solvents and moisture. |
Technical Specifications of N-Boc-D-Phenylalaninol
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 62–66°C |
| Optical Rotation | +18.0 to +22.0° (c=1, in CHCl3) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of N-Boc-D-Phenylalaninol
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of N-Boc-D-Phenylalaninol
Packaging of N-Boc-D-Phenylalaninol
Industrial N-Boc-D-Phenylalaninol Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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