China Factory Direct
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| CAS number | 106614-28-2 |
| Product name | METHYL 2,4-DIFLUOROBENZOATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of the antifungal drug voriconazole | Used to construct the triazole core structure via nucleophilic substitution and cyclization with methyl 2,4-difluorobenzoate |
| Agrochemicals | Structural building block for novel fluorinated benzamide fungicides (e.g., analogues of fluxapyroxad) | Used to introduce active side chains through multi-step reactions including aminolysis, amidation, chlorination, and coupling |
| Materials Science | Fluorinated aryl ester precursor for liquid crystal monomers or OLED hole-transport materials | Used to install conjugated frameworks via palladium-catalyzed cross-coupling (e.g., Suzuki or Heck reactions), followed by hydrolysis or transesterification |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, state, and presence of visible impurities under natural light or standard illumination. |
| Content (Purity) | High-Performance Liquid Chromatography (HPLC) | Utilize a reversed-phase C18 column with methanol-water or acetonitrile-water as the mobile phase, detect using a UV detector (e.g., 254 nm), and calculate the main component content by external standard or area normalization method. |
| Gas Chromatography (GC) | Applicable to samples with good volatility; separate using a capillary column and detect with an FID detector, calculating purity based on peak area. | |
| Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Analyze the chemical environment of hydrogen and fluorine atoms using ¹H NMR and ¹⁹F NMR to confirm molecular structure. |
| Fourier Transform Infrared Spectroscopy (FT-IR) | Measure the infrared absorption spectrum of the sample and compare it with reference spectra to confirm the presence of characteristic functional groups (e.g., ester groups, aromatic rings, C-F bonds). | |
| Residual Solvents | Gas Chromatography (GC) | According to the Chinese Pharmacopoeia or ICH guidelines, use headspace-GC to detect residual solvents such as methanol, ethanol, acetone, and dichloromethane. |
| Water Content | Karl Fischer Titration | Utilize the quantitative reaction between iodine and sulfur dioxide in the presence of pyridine and methanol with water to determine water content in the sample. |
| Melting Point / Boiling Point | Melting Point Apparatus / Differential Scanning Calorimetry (DSC) | Measure the melting temperature range to preliminarily assess purity and material consistency; DSC provides more precise phase transition information. |
| Related Substances (Impurities) | HPLC or GC | Separate and detect potential synthetic intermediates, by-products, or degradation products using gradient elution or programmed temperature rise to evaluate the impurity profile. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Detect heavy metal residues such as lead, arsenic, cadmium, and mercury to meet pharmaceutical or export standards. |
| Chlorides / Sulfates | Ion Chromatography (IC) or Turbidimetry | Ion chromatography precisely measures inorganic anion content; turbidimetry is used for rapid semi-quantitative detection of chloride or sulfate impurities. |
| Test Item | Specification |
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| Appearance | Colorless to light yellow clear liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Refractive Index (n20/D) | 1.515–1.525 |
| Relative Density (20°C/25°C) | 1.210–1.230 g/cm³ |
| Odor | Characteristic ester-like odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.