5-Amino-2-(trifluoromethyl)pyridine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 106877-33-2 |
| Product name | 5-Amino-2-(trifluoromethyl)pyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-Amino-2-(trifluoromethyl)pyridine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-Amino-2-(trifluoromethyl)pyridine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-Amino-2-(trifluoromethyl)pyridine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for anticancer agents (e.g., EGFR inhibitors) | Pyridine ring side chains are constructed via nitro group reduction or substitution reactions, followed by trifluoromethylation or direct cyclization using CF₃-containing precursors |
| Agrochemicals | Used in the synthesis of novel insecticides and herbicides (e.g., selective acetolactate synthase inhibitors) | Serves as a heterocyclic scaffold in coupling reactions (e.g., Suzuki, Buchwald–Hartwig) to introduce biologically active substituents |
| Materials Science | Building block for electron-transport materials in organic light-emitting diodes (OLEDs) | Halogen–metal exchange followed by coupling with boronic esters yields conjugated small molecules or polymers containing trifluoromethylpyridine units |
Manufacturing Quality Control of 5-Amino-2-(trifluoromethyl)pyridine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC with UV detection; identification based on retention time matching and relative response factors. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify common organic solvents (e.g., methanol, acetone, ethyl acetate) based on calibrated external standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent where water reacts stoichiometrically to determine trace moisture content. |
| Heavy Metals | ICP-MS | Multi-element detection and quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry for sub-ppq sensitivity. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column with suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Incineration at 700-750 C followed by weighing of residual inorganic ash after treatment with sulfuric acid. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid phase transition temperature using calibrated capillary apparatus under controlled heating rate. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light induced by chiral centers in solution, reported as degrees per dm per g/mL. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity patterns to calculate volume-based particle size distribution in dry or wet dispersion. |
| pH of Aqueous Suspension | pH Meter | Measurement of hydrogen ion activity in a standardized suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
| Residual Catalyst (Pd) | ICP-OES | Quantification of palladium residue after microwave-assisted acid digestion using inductively coupled plasma optical emission spectrometry. |
Technical Specifications of 5-Amino-2-(trifluoromethyl)pyridine
| Test Item | Specification |
|---|---|
| Appearance | Orange solid |
| Purity | >=98.5% (GC) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 58-62°C |
| Identification (NMR) | Conforms to reference standard |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-Amino-2-(trifluoromethyl)pyridine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-Amino-2-(trifluoromethyl)pyridine
Safety Information of 5-Amino-2-(trifluoromethyl)pyridine
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 5-Amino-2-(trifluoromethyl)pyridine
Industrial 5-Amino-2-(trifluoromethyl)pyridine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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