Methyl 4-amino-3-bromobenzoate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 106896-49-5 |
| Product name | Methyl 4-amino-3-bromobenzoate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Methyl 4-amino-3-bromobenzoate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Methyl 4-amino-3-bromobenzoate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Methyl 4-amino-3-bromobenzoate
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Antitumor drug intermediate | Used to synthesize pyrrolo[2,3-d]pyrimidine derivatives by coupling reactions to construct the pharmacophore scaffold |
| Pharmaceuticals | Key precursor for tyrosine kinase inhibitors | Employs Suzuki coupling to introduce aryl groups for targeted anticancer drug synthesis |
| Chemical | Drug molecule building block | Serves as a versatile synthon for structural modification in multistep organic synthesis |
| Research | Medicinal chemistry research tool | Applied in high-throughput screening library construction via nucleophilic substitution or condensation reactions to generate candidate compounds |
Manufacturing Quality Control of Methyl 4-amino-3-bromobenzoate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3A/B. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify methanol, dichloromethane, and other process solvents against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content via stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of Pb, Cd, Hg, As, and other regulated metals after acid digestion and matrix-matched calibration. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous extract; quantified against NaCl calibration curve. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after high-temperature ashing at 700-800 C and weighing. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature range using calibrated capillary apparatus per USP <741>. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light in solution to confirm chiral integrity and absence of racemization. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled white light against established reference standard. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode per USP <791>. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder size distribution by measuring angular scattering pattern of laser beam through dispersed sample. |
Technical Specifications of Methyl 4-amino-3-bromobenzoate
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Total Impurities | <=2.0% (by LC-MS) |
| Single Impurity | <=0.5% (by LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 128–132°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Methyl 4-amino-3-bromobenzoate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Methyl 4-amino-3-bromobenzoate
Safety Information of Methyl 4-amino-3-bromobenzoate
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of Methyl 4-amino-3-bromobenzoate
Industrial Methyl 4-amino-3-bromobenzoate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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