China Factory Direct
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| CAS number | 106930-51-2 |
| Product name | BOC-D-LEUCINOL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral synthetic intermediate | Used to synthesize drug molecules with specific stereochemistry, introducing the D-leucine structural unit via deprotection |
| Organic synthesis | Protecting group reagent | Applied in peptide or complex molecule synthesis to protect amino groups using BOC (tert-butoxycarbonyl), enhancing reaction selectivity and stability |
| Biochemistry | Drug candidate construction | Employed in asymmetric synthesis processes as a key chiral building block for preparing protease inhibitors or receptor antagonists |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 210 nm, comparing peak area to a certified reference standard. |
| Chiral Purity | Chiral HPLC | Separates D- and L-enantiomers on a chiral stationary phase; D-isomer content calculated from enantiomeric peak area ratio. |
| Residual Solvents | GC-FID | Detects and quantifies volatile organic solvents (e.g., THF, ethyl acetate) using gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Measures trace water via coulometric or volumetric titration based on iodine consumption in a pyridine-methanol buffer. |
| Heavy Metals | ICP-MS | Quantifies trace metal impurities (e.g., Pb, Cd, Ni) by plasma ionization and mass spectrometric detection. |
| Residual Palladium | ICP-OES | Determines palladium residue from catalytic hydrogenation using inductively coupled plasma optical emission spectroscopy. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column with suppressed conductivity detection. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using controlled heating and visual observation. |
| Optical Rotation | [alpha]D Measurement | Measures specific rotation at 589 nm using sodium D-line light to confirm chiral integrity and concentration. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of visible particulates or foreign matter under controlled lighting. |
| Loss on Drying | Gravimetric Analysis | Determines volatile content by measuring weight loss after drying under specified temperature and vacuum conditions. |
| Related Substances | HPLC-UV (Forced Degradation) | Identifies and quantifies structurally related impurities (e.g., de-BOC product, oxidation byproducts) using stability-indicating HPLC method. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.0% (GC-MS) |
| Optical Rotation | +22.8 to +28.3° (c=1, in methanol) |
| Melting Point | 58.0 to 62.0°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.