China Factory Direct
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| CAS number | 107-96-0 |
| Product name | 3-Mercaptopropionic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial GradeReagent Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Cosmetics | Used as a reducing agent in permanent-wave solutions to cleave disulfide bonds in keratin | Functions similarly to thioglycolic acid by reducing disulfide bonds in hair keratin to achieve curl formation and setting |
| Polymer Industry | Used as a chain transfer agent for acrylic polymers | Controls molecular weight and molecular weight distribution during free-radical polymerization |
| Pharmaceutical Intermediates | Used in the synthesis of antitumor agents, metal chelating agents, and thiol-containing drugs | Serves as a thiol-containing side-chain building block in coupling or modification reactions |
| Electroplating Additives | Used as a component of acidic copper brighteners | Coordinates with copper ions to enhance deposit brightness and surface leveling |
| Rubber Industry | Used as an accelerator for vulcanization of natural and synthetic rubber | Accelerates the vulcanization reaction and improves crosslinking efficiency |
| Analytical Chemistry | Used as a metal ion chelating agent and colorimetric reagent | Forms stable complexes with metal ions such as Cu²⁺ and Hg²⁺ for detection or separation |
| Detection Item | Common Testing Methods | Method Overview |
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| Purity/Content Determination | High-Performance Liquid Chromatography (HPLC) | Reverse-phase C18 column is used with water-methanol or water-acetonitrile as the mobile phase, and ultraviolet detection (typically at 200–220 nm wavelength). The content of 3-mercaptopropionic acid is calculated using external standard method or area normalization. This method offers excellent separation efficiency, high sensitivity, and good reproducibility. |
| Thiol Group Content | Iodometric Titration | The thiol group (–SH) reacts quantitatively with iodine: 2R–SH + I₂ → R–S–S–R + 2HI. Excess iodine is titrated, or the generated HI is directly titrated to determine the thiol group content, thereby indirectly reflecting the purity of 3-mercaptopropionic acid. The procedure is simple and suitable for routine quality control. |
| Melting Point Determination | Capillary Melting Point Method | Sample is loaded into a melting point capillary and heated slowly in a melting point apparatus. Initial and final melting temperatures are observed and recorded. The standard melting point range for 3-mercaptopropionic acid is approximately 75–78°C; deviation from this range may indicate the presence of impurities. |
| pH Value | pH Meter Measurement | A solution of 3-mercaptopropionic acid (e.g., 1% w/v) is prepared and its pH is measured at 25°C using a calibrated pH meter. The normal pH range is approximately 2.0–4.0, which reflects acidity strength and potential presence of basic impurities. |
| Moisture Content | Karl Fischer Titration | Water in the sample is quantitatively reacted with Karl Fischer reagent using either the volumetric or coulometric method. This technique is highly specific and accurate, making it ideal for determining low moisture levels in organic acid samples. |
| Heavy Metal Residue | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | After sample digestion, AAS or ICP-MS is used to determine the concentrations of heavy metals such as lead, arsenic, mercury, and cadmium, ensuring compliance with pharmacopoeial or chemical safety standards (e.g., ≤10 ppm). |
| Related Substances / Impurity Profiling | HPLC-UV or LC-MS | Gradient elution HPLC combined with UV or mass spectrometry detection is employed to identify and quantify impurity peaks other than the main component peak, assessing levels of degradation products (e.g., dimers, oxidation products) and other organic impurities. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow clear liquid |
| Purity | >=98.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Acid Value (mg KOH/g) | 175–185 mg KOH/g |
| Refractive Index (n20/D) | 1.462–1.466 |
| Relative Density (20°C/25°C) | 1.180–1.186 g/cm³ |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Odor | Characteristic sulfurous odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.