China Factory Direct
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| CAS number | 1070-83-3 |
| Product name | 3,3-Dimethylbutyric acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty GradeCosmetic GradeFood Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of pharmaceutical intermediates | Used as a key chiral building block in the synthesis of γ-aminobutyric acid (GABA) analogues, such as the antiepileptic drug pregabalin |
| Fine Fragrances | Raw material for fragrances and flavorings | Applied in synthesizing ester derivatives with fruity or floral notes, for use in cosmetic and food flavor formulations |
| Pesticides | Intermediate for agrochemicals | Employed in structural modification during the synthesis of certain insecticides or plant growth regulators to enhance biological activity |
| Organic Synthesis | Reagent for organic synthesis | Utilized as a carboxylic acid-based building block in acylation, esterification, and metal-catalyzed coupling reactions |
| Detection Item | Common Testing Methods | Method Overview |
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| Purity/Content Determination | Gas Chromatography (GC) | Capillary column gas chromatography with FID (Flame Ionization Detector) is used. The main component content of 3,3-dimethylbutyric acid is quantitatively analyzed by comparing retention times and peak areas with those of reference standards. Samples are typically dissolved in appropriate organic solvents (e.g., ethanol or ether) prior to injection. |
| Purity/Content Determination | High-Performance Liquid Chromatography (HPLC) | Reverse-phase C18 column is employed with UV detector (wavelength usually set at ~210 nm). Gradient or isocratic elution is performed using mobile phases such as methanol-water or acetonitrile-water. The content of the main component is calculated via external standard method or area normalization method. This method is suitable for thermally unstable or non-volatile samples. |
| Identification Test | Fourier Transform Infrared Spectroscopy (FT-IR) | The infrared absorption spectrum of the sample is recorded and compared with characteristic functional group peaks (e.g., broad O–H stretching vibration of carboxylic acid at ~2500–3300 cm⁻¹, C=O stretching vibration at ~1710 cm⁻¹, and C–H stretching vibration at ~2900–3000 cm⁻¹) against a reference spectrum to confirm molecular structure. |
| Identification Test | Proton Nuclear Magnetic Resonance (¹H NMR) | ¹H NMR spectra are acquired in deuterated solvents (e.g., CDCl₃ or DMSO-d₆). Molecular structure is confirmed based on chemical shifts, integration areas, and coupling splitting patterns (e.g., tertiary butyl signal appears as a singlet at δ ≈ 1.2 ppm). |
| Moisture Content Determination | Karl Fischer Titration | Either volumetric or coulometric Karl Fischer titration is applied to accurately determine trace moisture levels in the sample. This method is suitable for quality control requirements sensitive to water content. |
| Acid Value Determination | Acid-Base Titration | The sample is dissolved in neutral ethanol, and titrated with standardized sodium hydroxide solution using phenolphthalein as indicator until a faint pink endpoint is reached. The acid value (mg KOH/g) is calculated, indirectly reflecting free carboxylic acid content and purity. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Residual organic solvents (e.g., methanol, acetone, ethyl acetate) are analyzed via headspace injection. GC-FID is used for separation and detection, ensuring compliance with ICH Q3C guidelines regarding acceptable limits for residual solvents. |
| Heavy Metals/Inorganic Impurities | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectroscopy (AAS) | After sample digestion, concentrations of heavy metals such as lead, arsenic, cadmium, and mercury are determined to ensure compliance with pharmacopoeial or regulatory limits for inorganic impurities. |
| Test Item | Specification |
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| Appearance | Yellow liquid |
| Purity | >=98.0% (GC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Acid Value (mg KOH/g) | 175–185 mg KOH/g |
| Refractive Index (n20/D) | 1.415–1.425 |
| Relative Density (20°C/25°C) | 0.905–0.915 g/cm³ |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.